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NUMB antibody (Middle Region)
NUMB
Reactivity: Human, Mouse, Rat, Dog, Guinea Pig, Horse, Rabbit, Zebrafish (Danio rerio), Saccharomyces cerevisiae
WB
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-NUMB Antibody
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Target
See all NUMB Antibodies
NUMB
(Numb Homolog (NUMB))
Binding Specificity
All epitopes for NUMB antibodies
Middle Region
Reactivity
All reactivities for NUMB antibodies
Human, Mouse, Rat, Dog, Guinea Pig, Horse, Rabbit, Zebrafish (Danio rerio), Saccharomyces cerevisiae
Host
All hosts for NUMB antibodies
Rabbit
Clonality
All clonalities for NUMB antibodies
Polyclonal
Conjugate
All conjugates for NUMB antibodies
This NUMB antibody is un-conjugated
Application
All applications for NUMB antibodies
Western Blotting (WB)
Sequence
VGSSVAPGNT APSPSSPTSP TSDATTSLEM NNPHAIPRRH APIEQLARQG
Predicted Reactivity
Dog: 100%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 100%, Yeast: 91%, Zebrafish: 83%
Characteristics
This is a rabbit polyclonal antibody against NUMB. It was validated on Western Blot.
Purification
Affinity Purified
Immunogen
The immunogen is a synthetic peptide directed towards the middle region of Human NUMB
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Discover our top product NUMB Primary Antibody
Alternatives
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Application Details
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Restrictions
For Research Use only
Handling
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Format
Liquid
Concentration
1 mg/mL
Buffer
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
Avoid repeat freeze-thaw cycles.
Storage
-20 °C
Storage Comment
For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Target Details for NUMB
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Target
NUMB
(Numb Homolog (NUMB))
Alternative Name
NUMB (NUMB Products )
Synonyms
C14orf41 antibody, S171 antibody, c14_5527 antibody, Nb antibody, NUMB, endocytic adaptor protein antibody, numb homolog (Drosophila) antibody, NUMB antibody, Numb antibody, numb antibody
Background
The protein encoded by this gene plays a role in the determination of cell fates during development. The encoded protein, whose degradation is induced in a proteasome-dependent manner by MDM2, is a membrane-bound protein that has been shown to associate with EPS15, LNX1, and NOTCH1. Four transcript variants encoding different isoforms have been found for this gene. Protein Interaction Partner: TP53, PRKCA, PRKCZ, PRKCE, PRKCB, UBC, SIAH1, RPL3, EGFR, NOTCH1, MDM2, APP, Trp53, Jun, EPS15, Lnx1, ITCH, GLI1, LNX2, AP2A2, PRKCH, DPYSL2, AP2A1, ITGB2, L1CAM, PRKCG, PRKCD, ITGB3, ITGB5, Eps15l1, RALBP1, Protein Size: 592
Molecular Weight
64 kDa
Gene ID
8650
Pathways
Cell-Cell Junction Organization
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