CYP11B1 antibody (C-Term)
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- Target See all CYP11B1 Antibodies
- CYP11B1 (Cytochrome P450, Family 11, Subfamily B, Polypeptide 1 (CYP11B1))
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Binding Specificity
- C-Term
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Reactivity
- Human, Pig, Sheep
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This CYP11B1 antibody is un-conjugated
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Application
- Western Blotting (WB), Immunohistochemistry (IHC)
- Sequence
- ARNPNVQQAL RQESLAAAAS ISEHPQKATT ELPLLRAALK ETLRLYPVGL
- Predicted Reactivity
- Human: 100%, Pig: 79%, Sheep: 79%
- Characteristics
- This is a rabbit polyclonal antibody against CYP11B1. It was validated on Western Blot.
- Purification
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the C terminal region of human CYP11B1
- Top Product
- Discover our top product CYP11B1 Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 503 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- CYP11B1 (Cytochrome P450, Family 11, Subfamily B, Polypeptide 1 (CYP11B1))
- Alternative Name
- CYP11B1 (CYP11B1 Products)
- Synonyms
- CPN1 antibody, CYP11B antibody, FHI antibody, P450C11 antibody, AA389061 antibody, Cyp11b antibody, Cyp11b-1 antibody, Cp11ba antibody, RATCP11BA antibody, P450c11 antibody, cytochrome P450, family 11, subfamily B, polypeptide 1 antibody, cytochrome P450 family 11 subfamily B member 1 antibody, cytochrome P450, family 11, subfamily b, polypeptide 1 antibody, cytochrome P450, subfamily XI B, polypeptide 1 antibody, CYP11B1 antibody, Cyp11b1 antibody
- Background
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This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the mitochondrial inner membrane and is involved in the conversion of progesterone to cortisol in the adrenal cortex. Mutations in this gene cause congenital adrenal hyperplasia due to 11-beta-hydroxylase deficiency. Transcript variants encoding different isoforms have been noted for this gene.
Alias Symbols: CPN1, CYP11B, DKFZp686B05283, FHI, FLJ36771, P450C11
Protein Interaction Partner: CYP11B2,
Protein Size: 503 - Molecular Weight
- 55 kDa
- Gene ID
- 1584
- NCBI Accession
- NM_000497, NP_000488
- UniProt
- P15538
- Pathways
- Metabolism of Steroid Hormones and Vitamin D, Steroid Hormone Biosynthesis, Regulation of Systemic Arterial Blood Pressure by Hormones, C21-Steroid Hormone Metabolic Process, Carbohydrate Homeostasis
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