Ephrin A5 antibody (Middle Region)
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- Target See all Ephrin A5 (EFNA5) Antibodies
- Ephrin A5 (EFNA5)
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Binding Specificity
- Middle Region
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Reactivity
- Human, Rat, Mouse, Cow, Rabbit, Dog, Horse, Guinea Pig, Zebrafish (Danio rerio)
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This Ephrin A5 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- FDGYSACDHT SKGFKRWECN RPHSPNGPLK FSEKFQLFTP FSLGFEFRPG
- Predicted Reactivity
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 86%
- Characteristics
- This is a rabbit polyclonal antibody against EFNA5. It was validated on Western Blot.
- Purification
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of Human EFNA5
- Top Product
- Discover our top product EFNA5 Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 228 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- Ephrin A5 (EFNA5)
- Alternative Name
- EFNA5 (EFNA5 Products)
- Synonyms
- EFNA5 antibody, af1 antibody, efl5 antibody, rags antibody, eplg7 antibody, lerk7 antibody, AL-1 antibody, AV158822 antibody, EFL-5 antibody, Ephrin-A5 antibody, Epl7 antibody, LERK-7 antibody, RAGS antibody, Lerk7 antibody, AF1 antibody, EFL5 antibody, EPLG7 antibody, GLC1M antibody, LERK7 antibody, ephrin A5 antibody, EFNA5 antibody, efna5 antibody, Efna5 antibody
- Background
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Ephrin-A5, a member of the ephrin gene family, prevents axon bundling in cocultures of cortical neurons with astrocytes, a model of late stage nervous system development and differentiation. The EPH and EPH-related receptors comprise the largest subfamily of receptor protein-tyrosine kinases and have been implicated in mediating developmental events, particularly in the nervous system. EPH receptors typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin ligands and receptors have been named by the Eph Nomenclature Committee (1997). Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. The Eph family of receptors are similarly divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands.
Alias Symbols: AF1, EFL5, EPLG7, GLC1M, LERK7, RAGS
Protein Interaction Partner: MYC, GRIP1, SRC, EPHA7, EPHA4, EPHB2, EPHB1, EPHA5, EPHA3, EPHA2, EPHA8,
Protein Size: 228 - Molecular Weight
- 24 kDa
- Gene ID
- 1946
- NCBI Accession
- NM_001962, NP_001953
- UniProt
- P52803
- Pathways
- RTK Signaling
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