CFHR5 antibody (Center)

Catalog No. ABIN2794749

Product Details anti-CFHR5 Antibody

Target: CFHR5 (Complement Factor H-Related 5 (CFHR5))

Binding Specificity: AA 203-231, Center

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CFHR5 antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (IHC)

Purpose: Rabbit Anti-Human CFHR5 (Center) Antibody

Immunogen: This CFHR5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 203-231 amino acids from the Central region of human CFHR5.

Isotype: Ig Fraction

Application Details

Application Notes: Western Blot, Immunohistochemistry, Flow Cytometry
Recommended Dilutions
WB: 1:1000, IHC: 1:10-50, FC: 1:10-50CFHR5 Antibody (Center) .FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Storage: 4 °C,-20 °C

Storage Comment: 2-8°C (short-term), -20°C (long-term)

Target Details for CFHR5

Target: CFHR5 (Complement Factor H-Related 5 (CFHR5))

Alternative Name: CFHR5 (CFHR5 Products)

Synonyms: CFHL5 antibody, CFHR5D antibody, FHR-5 antibody, FHR5 antibody, complement factor H related 5 antibody, CFHR5 antibody

Background:

Target Description: CFHR5 is a member of a small complement factor H (CFH) gene cluster on chromosome 1. Each member of this gene family contains multiple short consensus repeats (SCRs) typical of regulators of complement activation. The protein encoded by this gene has nine SCRs with the first two repeats having heparin binding properties, a region within repeats 5-7 having heparin binding and C reactive protein binding properties, and the C-terminal repeats being similar to a complement component 3 b (C3b) binding domain. This protein co-localizes with C3, binds C3b in a dose-dependent manner, and is recruited to tissues damaged by C-reactive protein. Allelic variations in this gene have been associated, but not causally linked, with two different forms of kidney disease: membranoproliferative glomerulonephritis type II (MPGNII) and hemolytic uraemic syndrome (HUS). [provided by RefSeq].

Gene Symbol: CFHR5

Molecular Weight: 64419 Da

Gene ID: 81494

UniProt: Q9BXR6