PITRM1 antibody (Center)

Catalog No. ABIN2797735

Product Details anti-PITRM1 Antibody

Target: PITRM1 (Pitrilysin Metallopeptidase 1 (PITRM1))

Binding Specificity: AA 490-518, Center

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PITRM1 antibody is un-conjugated

Application: Western Blotting (WB)

Purpose: Rabbit Anti-Human PITRM1 (Center) Antibody

Immunogen: This PITRM1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 490-518 amino acids from the Central region of human PITRM1.

Isotype: Ig Fraction

Application Details

Application Notes: Western Blot
Recommended Dilutions
WB: 1:1000PITRM1 Antibody (Center) .

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.260 mg/mL

Storage: 4 °C,-20 °C

Storage Comment: 2-8°C (short-term), -20°C (long-term)

Target Details for PITRM1

Target: PITRM1 (Pitrilysin Metallopeptidase 1 (PITRM1))

Alternative Name: PITRM1 (PITRM1 Products)

Synonyms: MP1 antibody, PreP antibody, 2310012C15Rik antibody, AA410010 antibody, MP-1 antibody, Ntup1 antibody, mKIAA1104 antibody, PITRM1 antibody, wu:fa03d09 antibody, zgc:55469 antibody, pitrilysin metallopeptidase 1 antibody, pitrilysin metallepetidase 1 antibody, pitrilysin metallopeptidase 1 L homeolog antibody, PITRM1 antibody, Pitrm1 antibody, pitrm1.L antibody, pitrm1 antibody

Background:

Target Description: ATP-independent protease that degrades mitochondrial transit peptides after their cleavage. Also degrades other unstructured peptides. Specific for peptides in the range of 10 to 65 residues. Able to degrade amyloid beta A4 (APP) protein when it accumulates in mitochondrion, suggesting a link with Alzheimer disease. Shows a preference for cleavage after small polar residues and before basic residues, but without any positional preference.

Gene Symbol: PITRM1

Molecular Weight: 117413 Da

Gene ID: 10531

UniProt: Q5JRX3

Pathways: PI3K-Akt Signaling, SARS-CoV-2 Protein Interactome