Retinoic Acid Receptor beta antibody
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- Target See all Retinoic Acid Receptor beta (RARB) Antibodies
- Retinoic Acid Receptor beta (RARB) (Retinoic Acid Receptor, beta (RARB))
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This Retinoic Acid Receptor beta antibody is un-conjugated
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Application
- Western Blotting (WB)
- Cross-Reactivity
- Human
- Characteristics
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Rabbit Polyclonal antibody to Retinoic Acid Receptor beta (retinoic acid receptor, beta)
Retinoic Acid Receptor beta antibody - Purification
- Purified by antigen-affinity chromatography.
- Immunogen
- Recombinant protein encompassing a sequence within the center region of human Retinoic Acid Receptor beta. The exact sequence is proprietary.
- Isotype
- IgG
- Top Product
- Discover our top product RARB Primary Antibody
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- Application Notes
- WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
- Comment
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Positive Control: HepG2
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.97 mg/mL
- Buffer
- 1XPBS ( pH 7), 1 % BSA, 20 % Glycerol, 0.01 % Thimerosal
- Preservative
- Thimerosal (Merthiolate)
- Precaution of Use
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C,-20 °C
- Storage Comment
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- Target
- Retinoic Acid Receptor beta (RARB) (Retinoic Acid Receptor, beta (RARB))
- Alternative Name
- retinoic acid receptor beta (RARB Products)
- Synonyms
- RARB antibody, nRARs antibody, HAP antibody, NR1B2 antibody, RRB2 antibody, A830025K23 antibody, Hap antibody, Nr1b2 antibody, RARbeta2 antibody, RARBETA antibody, retinoic acid receptor beta antibody, retinoic acid receptor, beta antibody, RARB antibody, Rarb antibody
- Background
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This gene encodes retinoic acid receptor beta, a member of the thyroid-steroid hormone receptor superfamily of nuclear transcriptional regulators. This receptor localizes to the cytoplasm and to subnuclear compartments. It binds retinoic acid, the biologically active form of vitamin A which mediates cellular signalling in embryonic morphogenesis, cell growth and differentiation. It is thought that this protein limits growth of many cell types by regulating gene expression. The gene was first identified in a hepatocellular carcinoma where it flanks a hepatitis B virus integration site. The gene expresses at least two transcript variants, one additional transcript has been described, but its full length nature has not been determined.
Cellular Localization: Isoform Beta-1: Nucleus , Isoform Beta-2: Nucleus , Isoform Beta-4: Cytoplasm - Molecular Weight
- 50 kDa
- Gene ID
- 5915
- UniProt
- P10826
- Pathways
- Nuclear Receptor Transcription Pathway, Retinoic Acid Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway
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