RGS17 antibody (AA 70-150)

Catalog No. ABIN7231022

The Rabbit Polyclonal anti-RGS17 antibody (ABIN7231022) specifically detects RGS17 in WB and ELISA. The antibody is reactive with Human and Mouse samples.

Quick Overview for RGS17 antibody (AA 70-150) (ABIN7231022)

Target: RGS17 (Regulator of G-Protein Signaling 17 (RGS17))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RGS17 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-RGS17 Antibody

Binding Specificity: AA 70-150

Purpose: Rabbit Anti-RGS17 Polyclonal Antibody

Specificity: The antibody detects endogenous levels of RGS17 protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human RGS17 protein at AA range: 70-150

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for RGS17

Target: RGS17 (Regulator of G-Protein Signaling 17 (RGS17))

Alternative Name: RGS17

Background: Regulator of G-protein signaling 17, RGS17RGS17 (Regulator Of G Protein Signaling 17) encodes a member of the regulator of G-protein signaling family. This protein contains a conserved, 120 amino acid motif called the RGS domain and a cysteine-rich region. The protein attenuates the signaling activity of G-proteins by binding to activated, GTP-bound G alpha subunits and acting as a GTPase activating protein (GAP), increasing the rate of conversion of the GTP to GDP. This hydrolysis allows the G alpha subunits to bind G beta/gamma subunit heterodimers, forming inactive G-protein heterotrimers, thereby terminating the signal.

Molecular Weight: 23kD

Gene ID: 26575

UniProt: Q9UGC6

Pathways: Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling