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BCL2L10 antibody

BCL2L10 Reactivity: Human WB, ICC, IF, IHC (p) Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2856828
  • Target See all BCL2L10 Antibodies
    BCL2L10 (BCL2-Like 10 (Apoptosis Facilitator) (BCL2L10))
    Reactivity
    • 20
    • 16
    • 15
    Human
    Host
    • 31
    • 4
    Rabbit
    Clonality
    • 32
    • 3
    Polyclonal
    Conjugate
    • 16
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This BCL2L10 antibody is un-conjugated
    Application
    • 14
    • 13
    • 13
    • 10
    • 8
    • 7
    • 7
    • 6
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Cross-Reactivity
    Human
    Characteristics
    Rabbit polyclonal antibody to BCL2L10 (BCL2-like 10 (apoptosis facilitator))
    BCL2L10 antibody [N2C2], Internal
    Purification
    Purified by antigen-affinity chromatography.
    Immunogen
    Carrier-protein conjugated synthetic peptide encompassing a sequence within the center region of human BCL2L10. The exact sequence is proprietary.
    Isotype
    IgG
    Top Product
    Discover our top product BCL2L10 Primary Antibody
  • Application Notes
    WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1.32 mg/mL
    Buffer
    1XPBS ( pH 7), 20 % Glycerol, 0.025 % ProClin 300
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Target
    BCL2L10 (BCL2-Like 10 (Apoptosis Facilitator) (BCL2L10))
    Alternative Name
    BCL2 like 10 (BCL2L10 Products)
    Synonyms
    BCL-B antibody, Boo antibody, Diva antibody, AA420380 antibody, AU023065 antibody, C85687 antibody, NR-13 antibody, mcl1l antibody, nr13 antibody, sb:cb78 antibody, BCL2 like 10 antibody, Bcl2-like 10 antibody, BCL2-like 10 (apoptosis facilitator) antibody, BCL2L10 antibody, Bcl2l10 antibody, bcl2l10 antibody
    Background
    The protein encoded by this gene belongs to the BCL-2 protein family. BCL-2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. The protein encoded by this gene contains conserved BH4, BH1 and BH2 domains. This protein can interact with other members of BCL-2 protein family including BCL2, BCL2L1/BCL-X(L), and BAX. Overexpression of this gene has been shown to suppress cell apoptosis possibly through the prevention of cytochrome C release from the mitochondria, and thus activating caspase-3 activation. The mouse counterpart of this protein is found to interact with Apaf1 and forms a protein complex with Caspase 9, which suggests the involvement of this protein in APAF1 and CASPASE 9 related apoptotic pathway.

    Cellular Localization: Mitochondrion , Nucleus membrane
    Molecular Weight
    22 kDa
    Gene ID
    10017
    UniProt
    Q9HD36
    Pathways
    Positive Regulation of Endopeptidase Activity
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