IFNB1 antibody (Interferon, beta 1, Fibroblast)

Catalog No. ABIN285830

Product Details anti-IFNB1 Antibody

Target: IFNB1

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IFNB1 antibody is un-conjugated

Application: Immunoprecipitation (IP), Immunohistochemistry (IHC), ELISA, Western Blotting (WB)

Characteristics: Rabbit polyclonal IFN beta antibody
Bioactivity: In an antiviral assay for interferon about 1 unit/mL of interferon is the quantity necessary to produce a cytopathic effect of 50 %

Immunogen: IFN beta antibody was raised in rabbit using human interferon beta as the immunogen.

Application Details

Application Notes: Optimal conditions should be determined byt he investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Neat Serum diluted in PBS, no preservatives.

Preservative: Without preservative

Handling Advice: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Storage: -80 °C

Storage Comment: Aliquot and store at -70 °C or lower.

References for anti-IFNB1 antibody (ABIN285830)

Matsumoto, Takahashi, Shiva, Kawanishi, Kremenik, Kato, Yano: "The reduction of voluntary physical activity after poly I:C injection is independent of the effect of poly I:C-induced interferon-beta in mice." in: Physiology & behavior, Vol. 93, Issue 4-5, pp. 835-41, 2008 (PubMed).

Target Details for IFNB1

Target: IFNB1

Alternative Name: IFN beta (IFNB1 Products)

Synonyms: IFB, IFF, IFNB, IFN-beta, Ifb, Ifnb, IFNb, interferon beta 1, interferon beta 1, fibroblast, interferon, beta 1, fibroblast, IFNB1, Ifnb1

Background: Interferons (IFNs) are proteins made and released by lymphocytes in response to the presence of pathogens-such as viruses, bacteria, or parasites-or tumor cells. They allow communication between cells to trigger the protective defenses of the immune system that eradicate pathogens or tumors.

Pathways: JAK-STAT Signaling, TCR Signaling, TLR Signaling, Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response, Positive Regulation of Endopeptidase Activity, Hepatitis C, Autophagy, Inflammasome