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NTRK3 antibody (Extracellular Domain)
NTRK3
Reactivity: Rat
WB
Host: Goat
Polyclonal
unconjugated
Product Details anti-NTRK3 Antibody
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Target
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NTRK3
(Neurotrophic tyrosine Kinase, Receptor, Type 3 (NTRK3))
Binding Specificity
All epitopes for NTRK3 antibodies
Extracellular Domain
Reactivity
All reactivities for NTRK3 antibodies
Rat
Host
All hosts for NTRK3 antibodies
Goat
Clonality
All clonalities for NTRK3 antibodies
Polyclonal
Conjugate
All conjugates for NTRK3 antibodies
This NTRK3 antibody is un-conjugated
Application
All applications for NTRK3 antibodies
Western Blotting (WB)
Cross-Reactivity
Human, Mouse (Murine)
Purification
Protein G affinity chromatography
Immunogen
TrkC antibody was raised in goat using the entire extracellular domain of rat TrkC receptor as the immunogen.
Isotype
IgG
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Alternatives
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anti-Neurotrophic tyrosine Kinase, Receptor, Type 3 (NTRK3) (C-Term) antibody
NTRK3
Reactivity: Human, Mouse, Rat, Pig, Cow, Guinea Pig, Horse, Rabbit, Zebrafish (Danio rerio)
WB
Host: Rabbit
Polyclonal
unconjugated
Application Details
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Application Notes
Optimal conditions should be determined byt he investigator.
Restrictions
For Research Use only
Handling
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Format
Liquid
Concentration
Lot specific
Buffer
0.1 M tris-glycine, pH 7.4, with 0.11 NaCl, 0.1 % NaN3 and 30 % glycerol.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Handling Advice
Avoid repeated freeze/thaw cycles. Dilute only prior to immediate use.
Storage
-20 °C
Storage Comment
Aliquot and store at -20 °C.
Target Details for NTRK3
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Target
NTRK3
(Neurotrophic tyrosine Kinase, Receptor, Type 3 (NTRK3))
Alternative Name
TrkC (NTRK3 Products )
Synonyms
TRKC antibody, gp145(trkC) antibody, trkC antibody, AW125844 antibody, Ntrk3_tv3 antibody, TrkC antibody, neurotrophic receptor tyrosine kinase 3 antibody, neurotrophic tyrosine kinase, receptor, type 3 antibody, NTRK3 antibody, Ntrk3 antibody
Background
The Trk (tropomyosin-receptor-kinase) proto-oncogene family of receptor tyrosine kinases contains four members, TrkA, Tr kb, TrkC, and TrkE, which are variably expressed throughout the central and peripheral nervous systems. TrkC is the high affinity catalytic receptor for the neurotrophin NT-3 (neurotrophin-3). As such, TrkC mediates the multiple effects of this neurotrophic factor, which includes neuronal differentiation and survival.
Molecular Weight
145 kDa (predicted detection band MW)
Pathways
RTK Signaling , Neurotrophin Signaling Pathway , Regulation of Cell Size
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