IFNB1 antibody

Catalog No. ABIN289463

The Goat Polyclonal anti-IFNB1 antibody is suitable to detect IFNB1 in samples from Human. It has been validated for WB, ELISA and Neut.

Quick Overview for IFNB1 antibody (ABIN289463)

Target: IFNB1 (Interferon, beta 1, Fibroblast (IFNB1))

Reactivity: Human

Host: Goat

Clonality: Polyclonal

Conjugate: This IFNB1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Neutralization (Neut)

Product Details anti-IFNB1 Antibody

Characteristics: Affinity purified Goat polyclonal IFN beta antibody
Bioactivity: The exact concentration of antibody required to neutralize human interferon beta activity is dependent on the cytokine concentration, cell type, growth conditions and type of activity studied. The Neutralization Dose50 (ND50) for this antibody is defined as that concentration of antibody required to yield one-half maximal inhibition of the cytokine activity on a responsive cell line, when that cytokine is present at a concentration just high enough to elicit a maximum response. The ND50 for this antibody on human (HeLa/EMCV) cells is approx. 0.05- 0.2 µg/mL in the presence of 10ng/mL of human interferon beta, based on the anti-viral assay. The specific conditions are described in the figure legends.

Purification: Purified

Immunogen: IFN beta antibody was raised in goat using human interferon beta as the immunogen.

Isotype: IgG

Application Details

Application Notes: Optimal conditions should be determined byt he investigator.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Reconstitute in sterile PBS.

Concentration: Lot specific

Buffer: Lyophilized from PBS with 5 % trehalose.

Handling Advice: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Storage: -20 °C

Storage Comment: Aliquot and store at -20 °C.

Target Details for IFNB1

Target: IFNB1 (Interferon, beta 1, Fibroblast (IFNB1))

Alternative Name: IFN beta

Background: Interferons (IFNs) are proteins made and released by lymphocytes in response to the presence of pathogens-such as viruses, bacteria, or parasites-or tumor cells. They allow communication between cells to trigger the protective defenses of the immune system that eradicate pathogens or tumors.

Pathways: JAK-STAT Signaling, TCR Signaling, TLR Signaling, Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response, Positive Regulation of Endopeptidase Activity, Hepatitis C, Autophagy, Inflammasome