GRIN1/NMDAR1 antibody (AA 486-497)

Catalog No. ABIN295141

Product Details anti-GRIN1/NMDAR1 Antibody

Target: GRIN1/NMDAR1 (GRIN1) (Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 1 (GRIN1))

Binding Specificity: AA 486-497

Reactivity: Human, Rat, Mouse, Dog, Monkey, Xenopus laevis, Chicken, Cow, Zebrafish (Danio rerio), Hamster, Horse

Host: Goat

Clonality: Polyclonal

Conjugate: This GRIN1/NMDAR1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Specificity: Human GRIN1 / NMDAR1. This antibody is expected to recognise all three reported isoforms (NP_000823.4, NP_067544.1, NP_015566.1).

Predicted Reactivity: Percent identity by BLAST analysis: Human, Chimpanzee, Gibbon, Monkey, Marmoset, Mouse, Rat, Hamster, Panda, Bovine, Dog, Horse, Opossum, Turkey, Chicken, Platypus, Xenopus, Stickleback, Pufferfish, Zebrafish (100%).

Purification: Immunoaffinity purified

Immunogen: Synthetic peptide C-TQERVNNSNKKE from an internal region of human GRIN1 / NMDAR1 (NP_000823.4, NP_067544.1, NP_015566.1). Percent identity by BLAST analysis: Human, Chimpanzee, Gibbon, Monkey, Marmoset, Mouse, Rat, Hamster, Panda, Bovine, Dog, Horse, Opossum, Turkey, Chicken, Platypus, Xenopus, Stickleback, Pufferfish, Zebrafish (100%).

Type of Immunogen: Synthetic peptide

Application Details

Application Notes: Approved: Peptide-ELISA (1:1000), WB (1:1000, 2 - 4 μg/mL)

Not recommended for: IHC-P

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Tris-buffered saline,  pH 7.3, 0.5 % BSA, 0.02 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Minimize freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze-thaw cycles.

Target Details for GRIN1/NMDAR1

Target: GRIN1/NMDAR1 (GRIN1) (Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 1 (GRIN1))

Alternative Name: GRIN1 / NMDAR1 (GRIN1 Products)

Synonyms: GluN1 antibody, MRD8 antibody, NMDA1 antibody, NMDAR1 antibody, NR1 antibody, nmda1 antibody, nmdar1 antibody, GB19253 antibody, GRIN1 antibody, NMD-R1 antibody, Z16 antibody, GluRdelta1 antibody, GluRzeta1 antibody, M100174 antibody, Nmdar antibody, Rgsc174 antibody, NMDAR1.1 antibody, zgc:152678 antibody, glutamate ionotropic receptor NMDA type subunit 1 antibody, glutamate receptor, ionotropic, N-methyl D-aspartate 1 S homeolog antibody, NMDA receptor 1 antibody, G protein-regulated inducer of neurite outgrowth 1 antibody, glutamate receptor, ionotropic, NMDA1 (zeta 1) antibody, glutamate receptor, ionotropic, N-methyl D-aspartate 1a antibody, GRIN1 antibody, grin1.S antibody, grin1 antibody, Grin1 antibody, Nmdar1 antibody, Gprin1 antibody, grin1a antibody

Background: Name/Gene ID: GRIN1
Subfamily: Glutamate receptor - ionotropic (NMDA receptor)
Family: Ion Channel

Synonyms: GRIN1, GluN1, NMDAR1, NR1, MRD8, NMD-R1, NMDA receptor A1, NMDA1, NR1a, GluR zeta 1

Gene ID: 2902

NCBI Accession: NP_000823, NP_067544, NP_015566

UniProt: Q05586

Pathways: Synaptic Membrane, Feeding Behaviour, Regulation of long-term Neuronal Synaptic Plasticity