Reacts with human Fibroblast Growth Factor Receptor 1 (FGFR1).
Purification
Purified (protein G)
Immunogen
Recombinant human ectodomain of FGFr1beta expressed in E. coli beginning with proline 23, antigen contained NH2-terminal gly-ser-pro-gly-ile and COOH terminal glu-phe sequences.
FGFR1
Reactivity: Human
WB, ELISA, IF
Host: Rabbit
Polyclonal
unconjugated
Application Notes
Working dilution: Optimal dilution should be determined by the end user. The following are guidelines only : FC (1 μg/1x10.6 cells) IHC(1 μg/mL) WB(1 μg/mL)
Restrictions
For Research Use only
Buffer
PBS, pH 7.4
Handling Advice
Dilute in PBS or medium that is identical to that used in the assay system.
Storage
-20 °C/-80 °C
Storage Comment
Stable for at least one year at -20°C to -70°C. Avoid multiple freeze-thaw cycles.
Fibroblast Growth Factor Receptor 1 (FGFR1) is a member of the fibroblast growth factor receptor (FGFR) family, where amino acid sequence is highly conserved between members and throughout evolution. This protein is a Tyrosine-protein kinase that acts as cell-surface receptor for fibroblast growth factors and plays an essential role in the regulation of embryonic development, cell proliferation, differentiation and migration.