LAMP1 antibody

Catalog No. ABIN298674

Product Details anti-LAMP1 Antibody

Target: LAMP1 (Lysosomal-Associated Membrane Protein 1 (LAMP1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This LAMP1 antibody is un-conjugated

Application: Flow Cytometry (FACS)

Specificity: Recognizes human CD107a, otherwise known as LAMP-1 (lysosome-associated membrane protein-1), a 100-120kD type I integral lysosomal membrane glycoprotein and member of the LAMP family, which transfers between lysosomes, phagosomes and the plasma membrane, and may play a role in lysosomal membrane protection and in lectin-mediated cell adhesion. Studies have linked enhanced CD107a expression with the metastatic potential of some tumor cells, and with neurons and glial cells surrounding plaques in Alzheimer's patients. CD107a may also serve as a marker of mast cell activation.

Purification: Ion exchange chromatography

Immunogen: Human U937 Caucasian hystiocytic lymphoma cell line.

Type of Immunogen: Cells

Clone: B-T47

Isotype: IgG1

Application Details

Application Notes: Approved: Flo

Usage: Flow Cytometry: Use 10 μL of the suggested working dilution to label 1x10^6 cells in 100 μL. Method sheets are available on request. The applications listed have been tested for the unmodified form of this product. Other forms have not been tested.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: PBS,  pH 7.4.

Preservative: Azide free

Storage: -20 °C

Storage Comment: Short term: -20°C
Long term: -20°C.

Target Details for LAMP1

Target: LAMP1 (Lysosomal-Associated Membrane Protein 1 (LAMP1))

Alternative Name: LAMP1 / CD107a (LAMP1 Products)

Synonyms: CD107a antibody, LAMPA antibody, LGP120 antibody, AI196048 antibody, Lamp-1 antibody, LEP100 antibody, LAMP-1 antibody, LGP-A antibody, Lgpa antibody, Lysosome-associated membrane protein 1 antibody, cd107a antibody, lamp-1 antibody, lamp1 antibody, lampa antibody, lgp120 antibody, rexp76 antibody, lysosomal associated membrane protein 1 antibody, lysosomal-associated membrane protein 1 antibody, lysosomal-associated membrane protein 1 L homeolog antibody, LAMP1 antibody, Lamp1 antibody, lamp1.L antibody

Background: Name/Gene ID: LAMP1

Synonyms: LAMP1, CD107a, CD107a antigen, LAMP-1, LGP120, LAMPA

Gene ID: 3916

Pathways: Autophagy