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RAGE antibody (AA 30-330)
AGER
Reactivity: Human
WB
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-RAGE Antibody
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Target
See all RAGE (AGER) Antibodies
RAGE (AGER)
(Advanced Glycosylation End Product-Specific Receptor (AGER))
Binding Specificity
All epitopes for RAGE antibodies
AA 30-330
Reactivity
All reactivities for RAGE antibodies
Human
Host
All hosts for RAGE antibodies
Rabbit
Clonality
All clonalities for RAGE antibodies
Polyclonal
Conjugate
All conjugates for RAGE antibodies
This RAGE antibody is un-conjugated
Application
All applications for RAGE antibodies
Western Blotting (WB)
Sequence
IGEPLVLKCK GAPKKPPQRL EWKLNTGRTE AWKVLSPQGG GPWDSVARVL PNGSLFLPAV GIQDEGIFRC QAMNRNGKET KSNYRVRVYQ IPGKPEIVDS ASELTAGVPN KVGTCVSEGS YPAGTLSWHL DGKPLVPNEK GVSVKEQTRR HPETGLFTLQ SELMVTPARG GDPRPTFSCS FSPGLPRHRA LRTAPIQPRV WEPVPLEEVQ LVVEPEGGAV APGGTVTLTC EVPAQPSPQI HWMKDGVPLP LPPSPVLILP EIGPQDQGTY SCVATHSSHG PQESRAVSIS IIEPGEEGPT A
Cross-Reactivity
Human, Mouse, Rat
Characteristics
Polyclonal Antibodies
Purification
Affinity purification
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 30-330 of human AGER (NP_001127.1).
Isotype
IgG
Top Product
Discover our top product AGER Primary Antibody
Alternatives
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Application Details
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Application Notes
WB,1:500 - 1:2000
Restrictions
For Research Use only
Handling
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Format
Liquid
Buffer
PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
Avoid freeze / thaw cycles
Storage
-20 °C
Storage Comment
Store at -20°C. Avoid freeze / thaw cycles.
Target Details for RAGE
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Target
RAGE (AGER)
(Advanced Glycosylation End Product-Specific Receptor (AGER))
Alternative Name
AGER (AGER Products )
Synonyms
RAGE antibody, AGER antibody, advanced glycosylation end-product specific receptor antibody, advanced glycosylation end product-specific receptor antibody, MAPK/MAK/MRK overlapping kinase antibody, AGER antibody, Ager antibody, LOC719012 antibody
Background
The advanced glycosylation end product (AGE) receptor encoded by this gene is a member of the immunoglobulin superfamily of cell surface receptors. It is a multiligand receptor, and besides AGE, interacts with other molecules implicated in homeostasis, development, and inflammation, and certain diseases, such as diabetes and Alzheimer's disease. Many alternatively spliced transcript variants encoding different isoforms, as well as non-protein-coding variants, have been described for this gene (PMID:18089847).,AGER,RAGE,SCARJ1,Endocrine & Metabolism,Endocrine and metabolic diseases,Diabetes,Immunology & Inflammation,Neuroscience,Neurodegenerative Diseases,Amyloid Plaque and Neurofibrillary Tangle Formation in Alzheimer's Disease,Cardiovascular,AGER
Molecular Weight
13 kDa/35-44 kDa
Gene ID
177
UniProt
Q15109
Pathways
Carbohydrate Homeostasis , Toll-Like Receptors Cascades , Smooth Muscle Cell Migration , S100 Proteins
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