NTRK2
Reactivity: Human
WB, IHC, IF
Host: Mouse
Monoclonal
2E1
unconjugated
Application Notes
WB,1:500 - 1:2000,IF,1:50 - 1:200
Restrictions
For Research Use only
Format
Liquid
Buffer
PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
Avoid freeze / thaw cycles
Storage
-20 °C
Storage Comment
Store at -20°C. Avoid freeze / thaw cycles.
Hang, Sun, Guo, Zhao, Du: "BDNF-mediates Down-regulation of MicroRNA-195 Inhibits Ischemic Cardiac Apoptosis in Rats." in: International journal of biological sciences, Vol. 12, Issue 8, pp. 979-89, (2017) (PubMed).
Target
TRKB (NTRK2)
(Neurotrophic Tyrosine Kinase, Receptor, Type 2 (NTRK2))
This gene encodes a member of the neurotrophic tyrosine receptor kinase (NTRK) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. Signalling through this kinase leads to cell differentiation. Mutations in this gene have been associated with obesity and mood disorders. Alternative splicing results in multiple transcript variants.,NTRK2,GP145-TrkB,TRKB,trk-B,TrkB,OBHD,Cancer,Signal Transduction,Kinase,Tyrosine kinases,Cell Biology & Developmental Biology,Growth factor,Endocrine & Metabolism,Neuroscience,NTRK2