TRPV2
Reactivity: Mouse, Rat
WB, IHC, IF, IP
Host: Rabbit
Polyclonal
unconjugated
Application Notes
Immunohistochemistry on Paraffin Sections (10 μg/mL). Steam slides in 0.01 M sodium citrate buffer, pH 6.0, at 99-100 °C for 20 min. Remove fromheat and let stand at room temperature in buffer for 20 min. Rinse in 1x TBS with Tween(TBST) for 1 min. at room temperature. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions
For Research Use only
Concentration
0.8 mg/mL
Buffer
PBS containing 0.09 % Sodium Azide as preservative.
Preservative
Sodium azide
Precaution of Use
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
Avoid repeated freezing and thawing.
Storage
4 °C/-80 °C
Storage Comment
Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -70 °C for longer.
Transient receptor potential vanilloid (TRPV) channels are widely expressed in both sensory and nonsensory cells. TRPV2, a member of transient receptor potential ion channels, responds to high-threshold noxious heat (with a threshold of approximately 52 degrees C), but neither to capsaicin nor to proton. TRPV2 transcripts are not restricted to the sensory nervous system, indicating that this channel may be activated by stimuli other than heat. It has been proposed that responses to noxious heat involve these related, but distinct, ion-channel subtypes that together detect a range of stimulus intensities.Synonyms: OTRPC2, Osm-9-like TRP channel 2, Transient receptor potential cation channel subfamily V member 2, VRL, VRL-1, Vanilloid receptor-like protein 1