UCHL1 antibody

Catalog No. ABIN3026780

Product Details anti-UCHL1 Antibody

Target: UCHL1 (Ubiquitin Carboxyl-terminal Esterase L1 (Ubiquitin Thiolesterase) (UCHL1))

Reactivity: Human, Rat, Mouse, Cow, Pig, Guinea Pig, Dog, Rabbit, Zebrafish (Danio rerio), Sheep

Host: Mouse

Clonality: Monoclonal

Conjugate: This UCHL1 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Characteristics: This antibody specifically reacts with a protein of 20-30 kDa, identified as UchL1 (Ubiquitin carboxyl-terminal hydrolase-1), or PGP9.5. Studies using UchL1 antibody have shown that expression is related to tumor progression, with high expression correlating with poor prognosis, making the protein a potentially useful marker for pancreatic and invasive colorectal cancer. A mutation in gene is believed to cause a form of Parkinson's disease.

Purification: Protein G affinity chromatography

Immunogen: Native protein from brain was used as the immunogen for this UchL1 antibody.

Clone: 13C4

Isotype: IgG2a kappa

Application Details

Application Notes: The concentration stated for each application is a general starting point. Variations in protocols, secondaries and substrates may require the UchL1 antibody to be titered up or down for optimal performance.\. WB: 0.5-1 μg/mL,IF: 1-2 μg/mL

Restrictions: For Research Use only

Handling

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store the UchL1 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).

Target Details for UCHL1

Target: UCHL1 (Ubiquitin Carboxyl-terminal Esterase L1 (Ubiquitin Thiolesterase) (UCHL1))

Alternative Name: UchL1 PGP9.5 (UCHL1 Products)

Synonyms: PARK5 antibody, PGP 9.5 antibody, PGP9.5 antibody, PGP95 antibody, Uch-L1 antibody, UCH-L1 antibody, UCHL1 antibody, cb358 antibody, wu:fc55h08 antibody, park5 antibody, pgp9.5 antibody, uch-l1 antibody, MGC132191 antibody, uchl1 antibody, AW822034 antibody, C88048 antibody, R75593 antibody, UCHL-1 antibody, gad antibody, ubiquitin C-terminal hydrolase L1 antibody, ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) antibody, ubiquitin C-terminal hydrolase L1 L homeolog antibody, ubiquitin carboxyl-terminal esterase L1 antibody, ubiquitin carboxy-terminal hydrolase L1 antibody, UCHL1 antibody, uchl1 antibody, uchl1.L antibody, LOC100304750 antibody, Uchl1 antibody

Background: This antibody specifically reacts with a protein of 20-30  kDa, identified as UchL1 (Ubiquitin carboxyl-terminal hydrolase-1), or PGP9.5. Studies using UchL1 antibody have shown that expression is related to tumor progression, with high expression correlating with poor prognosis, making the protein a potentially useful marker for pancreatic and invasive colorectal cancer. A mutation in gene is believed to cause a form of Parkinson's disease.

Gene ID: 7345

Pathways: Feeding Behaviour