Kallikrein 10 antibody (C-Term)

Catalog No. ABIN3031526

Product Details anti-Kallikrein 10 Antibody

Target: Kallikrein 10 (KLK10)

Binding Specificity: C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Kallikrein 10 antibody is un-conjugated

Application: Western Blotting (WB)

Purification: Antigen affinity

Immunogen: An amino acid sequence from the C-terminus of human Kallikrein 10 (SAQHPAVYTQICKY) was used as the immunogen for this Kallikrein 10 antibody.

Isotype: IgG

Application Details

Application Notes: The stated application concentrations are suggested starting amounts. Titration of the Kallikrein 10 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL

Restrictions: For Research Use only

Handling

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: -20 °C

Storage Comment: After reconstitution, the Kallikrein 10 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Target Details for Kallikrein 10

Target: Kallikrein 10 (KLK10)

Alternative Name: Kallikrein 10 (KLK10 Products)

Synonyms: KLK10 antibody, 2300002A13Rik antibody, NES1 antibody, PRSSL1 antibody, kallikrein related peptidase 10 antibody, kallikrein related-peptidase 10 antibody, kallikrein-related peptidase 10 antibody, KLK10 antibody, Klk10 antibody

Background: Kallikrein-related peptidase 10, also known as KLK10, PRSSL1 or NES1, belongs to the kallikrein subfamily of serine proteases, which are involved in a variety of enzymatic processes. Its encoded protein is secreted and may play a role in suppression of tumorigenesis in breast and prostate cancers. KLK10 contains 12 conserved cysteines in its protease domain that are expected to form 6 disulfide bonds, as in other serine proteases. RT-PCR detected variable levels of KLK10 expression in nearly all of the 35 adult and fetal tissues examined. The gene contains 6 exons, the first of which is noncoding. By fluorescence in situ hybridization, Polikoff et al.(1997) mapped the gene to 19q13.3. By genomic sequence analysis,Gan et al.(2000) mapped the gene within the KLK gene cluster on chromosome 19q13. This cluster includes 13 KLK genes and 5 pseudogenes.

UniProt: O43240

Pathways: Complement System