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HLAG antibody
HLAG
Reactivity: Human
ELISA, FACS, IHC
Host: Mouse
Monoclonal
unconjugated
Product Details anti-HLAG Antibody
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Target
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HLAG
(HLA Class I Histocompatibility Antigen, alpha Chain G (HLAG))
Reactivity
All reactivities for HLAG antibodies
Human
Host
All hosts for HLAG antibodies
Mouse
Clonality
All clonalities for HLAG antibodies
Monoclonal
Conjugate
All conjugates for HLAG antibodies
This HLAG antibody is un-conjugated
Application
All applications for HLAG antibodies
ELISA, Flow Cytometry (FACS), Immunohistochemistry (IHC)
Specificity
The antibody 87G recognizes both membrane-bound and soluble forms of HLA-G (HLA-G1 and HLA-G5). HLA-G belongs to the MHC Class I molecules (MHC Class Ib, nonclassical) and it is expressed on the surface of trophoblast cells. The antibody 87G blocks interaction of HLA-G with inhibitory receptors.
Purification
Purified from cell culture supernatant by protein-A affinity chromatography
Immunogen
HLA-B27 transgenic mice were imunized with H-2 identical murine cells transfected with and expressing genes encoding HLA-G and Human beta2-microglobulin.
Isotype
IgG2a
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Alternatives
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Application Details
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Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Format
Liquid
Buffer
PBS with 15 mM sodium azide, approx. pH 7.4
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
4 °C
Storage Comment
Store at 2-8°C. Do not freeze.
Target Details for HLAG
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Target
HLAG
(HLA Class I Histocompatibility Antigen, alpha Chain G (HLAG))
Alternative Name
HLA-G (HLAG Products )
Synonyms
MHC-G antibody, B-F antibody, B-F-S04 antibody, B-F-S05 antibody, B-F-S06 antibody, B-F-S07 antibody, B-FI antibody, B-FIV antibody, BF2 antibody, BFa2 antibody, BFw-03 antibody, BFw-05 antibody, BFz-01 antibody, major histocompatibility complex, class I, G antibody, MHC BF1 class I antibody, HLA-G antibody, BF1 antibody
Gene ID
3135
Pathways
Regulation of Leukocyte Mediated Immunity , Positive Regulation of Immune Effector Process , Cancer Immune Checkpoints
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