CDK5 antibody (C-Term)
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- Target See all CDK5 Antibodies
- CDK5 (Cyclin-Dependent Kinase 5 (CDK5))
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Binding Specificity
- AA 273-292, C-Term
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Reactivity
- Human, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This CDK5 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Purpose
- Rabbit IgG polyclonal antibody for Cyclin-dependent-like kinase 5(CDK5) detection. Tested with WB in Human,Mouse,Rat.
- Sequence
- QRISAEEALQ HPYFSDFCPP
- Cross-Reactivity (Details)
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Predicted Cross Reactivity: mouse
No cross reactivity with other proteins.
Predicted Cross Reactivity: Species predicted to be fit for the product based on sequence similarities. - Characteristics
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Rabbit IgG polyclonal antibody for Cyclin-dependent-like kinase 5(CDK5) detection. Tested with WB in Human,Mouse,Rat.
Gene Name: cyclin-dependent kinase 5
Protein Name: Cyclin-dependent-like kinase 5 - Purification
- Immunogen affinity purified.
- Immunogen
- A synthetic peptide corresponding to a sequence at the C-terminus of human Cdk5(273-292aa QRISAEEALQHPYFSDFCPP), identical to the related rat and mouse sequence.
- Isotype
- IgG
- Top Product
- Discover our top product CDK5 Primary Antibody
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- Application Notes
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WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Rat, Predicted Species: Mouse
Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities.
Other applications have not been tested. Optimal dilutions should be determined by end users. - Comment
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
- Concentration
- 500 μg/mL
- Buffer
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.
- Preservative
- Thimerosal (Merthiolate), Sodium azide
- Precaution of Use
- This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freezing and thawing.
- Storage
- 4 °C/-20 °C
- Storage Comment
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At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing. - Expiry Date
- 12 months
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A new treatment for cognitive disorders related to in utero exposure to alcohol." in: Neural regeneration research, Vol. 8, Issue 18, pp. 1702-13, (2014) (PubMed).
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A new treatment for cognitive disorders related to in utero exposure to alcohol." in: Neural regeneration research, Vol. 8, Issue 18, pp. 1702-13, (2014) (PubMed).
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- Target
- CDK5 (Cyclin-Dependent Kinase 5 (CDK5))
- Alternative Name
- CDK5 (CDK5 Products)
- Synonyms
- PSSALRE antibody, AW048668 antibody, Crk6 antibody, CDK5 antibody, CG8203 antibody, DmCdk5 antibody, Dmel\\CG8203 antibody, cdk5 antibody, zgc:101604 antibody, cyclin dependent kinase 5 antibody, cyclin-dependent kinase 5 antibody, Cyclin-dependent kinase 5 antibody, cyclin-dependent kinase 5 L homeolog antibody, Cyclin-dependent-like kinase 5 antibody, CDK5 antibody, Cdk5 antibody, cdk5 antibody, cdk5.L antibody, cdk-5 antibody
- Background
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CDK5, Cyclin-Dependent Kinase5, is also know as PSSALRE. The p34(CDC2) protein kinase regulates important transitions in the eukaryotic cell cycle. The PSSALRE expression is in all human tissues and cell lines tested. The the CDK5 gene is mapped to chromosome 7q36. Cyclin-dependent kinase-5 is predominantly expressed in neurons where it phosphorylates both high molecular weight neurofilaments and microtubule-associated protein tau. CDK5 is required for proper development of the mammalian central nervous system. To be activated, CDK5 must associate with its regulatory subunit, p35(CDK5R1). CDK5 can phosphorylate DARPP32 at threonine-75, converting it into an inhibitor of PKA.
Synonyms: Cdk 5 antibody|Cdk5 antibody|CDK5_HUMAN antibody|Cell division protein kinase 5 antibody|Crk6 antibody|Cyclin dependent kinase 5 antibody|Cyclin-dependent kinase 5 antibody|Protein kinase CDK5 splicing antibody|PSSALRE antibody|Serine threonine protein kinase PSSALRE antibody|Serine/threonine-protein kinase PSSALRE antibody|Tau protein kinaseII catalytic subunit antibody|TPKII catalytic subunit antibody - UniProt
- Q00535
- Pathways
- Cell Division Cycle, Regulation of Muscle Cell Differentiation, Synaptic Membrane, Regulation of Cell Size, Skeletal Muscle Fiber Development, Synaptic Vesicle Exocytosis
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