HIF3A antibody (C-Term)
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- Target See all HIF3A Antibodies
- HIF3A (Hypoxia Inducible Factor 3, alpha Subunit (HIF3A))
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Binding Specificity
- AA 497-514, C-Term
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Reactivity
- Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This HIF3A antibody is un-conjugated
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Application
- Western Blotting (WB)
- Purpose
- Rabbit IgG polyclonal antibody for Hypoxia-inducible factor 3-alpha(HIF3A) detection. Tested with WB in Human,Rat.
- Sequence
- DDDFQLNASE QLPRAYHR
- Cross-Reactivity (Details)
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Predicted Cross Reactivity: human
No cross reactivity with other proteins.
Predicted Cross Reactivity: Species predicted to be fit for the product based on sequence similarities. - Characteristics
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Rabbit IgG polyclonal antibody for Hypoxia-inducible factor 3-alpha(HIF3A) detection. Tested with WB in Human,Rat.
Gene Name: hypoxia inducible factor 3, alpha subunit
Protein Name: Hypoxia-inducible factor 3-alpha - Purification
- Immunogen affinity purified.
- Immunogen
- A synthetic peptide corresponding to a sequence at the C-terminus of human HIF3(497-514aa DDDFQLNASEQLPRAYHR), different from the related rat and mouse sequences by five amino acids.
- Isotype
- IgG
- Top Product
- Discover our top product HIF3A Primary Antibody
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- Application Notes
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WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Rat, Predicted Species: Human
Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities.
Other applications have not been tested. Optimal dilutions should be determined by end users. - Comment
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
- Concentration
- 500 μg/mL
- Buffer
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.
- Preservative
- Thimerosal (Merthiolate), Sodium azide
- Precaution of Use
- This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freezing and thawing.
- Storage
- 4 °C/-20 °C
- Storage Comment
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At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing. - Expiry Date
- 12 months
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- Target
- HIF3A (Hypoxia Inducible Factor 3, alpha Subunit (HIF3A))
- Alternative Name
- HIF3A (HIF3A Products)
- Synonyms
- HIF-3A antibody, IPAS antibody, MOP7 antibody, PASD7 antibody, bHLHe17 antibody, Ipas antibody, NEPAS antibody, Mop7 antibody, HIF3A antibody, hypoxia inducible factor 3 alpha subunit antibody, hypoxia inducible factor 3, alpha subunit antibody, HIF3A antibody, Hif3a antibody
- Background
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Hypoxia-inducible factor 3 alpha, also called MOP7, is a protein that in humans is encoded by the HIF3A gene. HIF3A is mapped to 19q13.32. This gene involved in adaptive response to hypoxia. HIF3A suppresses hypoxia-inducible expression of HIF1A and EPAS1. It binds to core DNA sequence 5'-TACGTG-3' within the hypoxia response element(HRE) of target gene promoters. The complex HIF3A-ARNT activates the transcription of reporter genes driven by HRE. This gene functions as an inhibitor of angiogenesis in the cornea.
Synonyms: Basic-helix-loop-helix-PAS protein MOP7 antibody|bHLHe17 antibody|Class E basic helix-loop-helix protein 17 antibody|HIF 3A antibody|HIF 3A4 antibody|HIF-3-alpha antibody|HIF3 alpha antibody|HIF3-alpha antibody|HIF3-alpha-1 antibody|HIF3A antibody|HIF3A_HUMAN antibody|Hypoxia Inducible Factor 3 alpha antibody|Hypoxia inducible factor 3 alpha subunit antibody|Hypoxia inducible factor three alpha antibody|Hypoxia-inducible factor 3-alpha antibody|Inhibitory PAS domain protein antibody|IPAS antibody|Member of PAS protein 7 antibody|MOP7 antibody|PAS domain-containing protein 7 antibody|PASD7 antibody - UniProt
- Q9Y2N7
- Pathways
- Warburg Effect
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