TRIO antibody (C-Term)

Catalog No. ABIN3044556

Product Details anti-TRIO Antibody

Target: TRIO (Triple Functional Domain Protein (TRIO))

Binding Specificity: AA 787-830, C-Term

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TRIO antibody is un-conjugated

Application: Western Blotting (WB)

Purpose: Rabbit IgG polyclonal antibody for Triple functional domain protein(TRIO) detection. Tested with WB in Human,Mouse,Rat.

Sequence: QLRIFERDAI DIISDLESWN DELSQQMNDF DTEDLTIAEQ RLQH

Cross-Reactivity (Details): No cross reactivity with other proteins.

Characteristics: Rabbit IgG polyclonal antibody for Triple functional domain protein(TRIO) detection. Tested with WB in Human,Mouse,Rat.
Gene Name: trio Rho guanine nucleotide exchange factor
Protein Name: Triple functional domain protein

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human TRIO (787-830aa QLRIFERDAIDIISDLESWNDELSQQMNDFDTEDLTIAEQRLQH), identical to the related mouse and rat sequences.

Isotype: IgG

Application Details

Application Notes: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Mouse, Rat
Notes: Tested Species: Species with positive results.
Other applications have not been tested. Optimal dilutions should be determined by end users.

Comment:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Target Details for TRIO

Target: TRIO (Triple Functional Domain Protein (TRIO))

Alternative Name: TRIO (TRIO Products)

Synonyms: ARHGEF23 antibody, tgat antibody, 6720464I07Rik antibody, AA408740 antibody, Solo antibody, si:dz230d15.1 antibody, trio Rho guanine nucleotide exchange factor antibody, triple functional domain (PTPRF interacting) antibody, trio Rho guanine nucleotide exchange factor b antibody, TRIO antibody, Trio antibody, triob antibody

Background: Triple functional domain protein is a protein that in humans is encoded by the TRIO gene. This gene encodes a large protein that functions as a GDP to GTP exchange factor. This protein promotes the reorganization of the actin cytoskeleton, thereby playing a role in cell migration and growth. Additionally, the TRIO protein contains 3 functional domains: a serine/threonine kinase domain and 2 guanine nucleotide exchange factor (GEF) domains for the family of Rho-like GTPases, specific for Rac1 and RhoA, respectively. These domains suggest that this enzyme may play a key role in several signaling pathways that control cell proliferation.

Synonyms: ARHGEF23 antibody|PTPRF-interacting protein antibody|tgat antibody|trio antibody|TRIO_HUMAN antibody|Triple functional domain protein antibody

Gene ID: 7204

UniProt: O75962