c-MYC antibody

Catalog No. ABIN306633

The Mouse Monoclonal anti-c-MYC antibody (Clone 4C6-1) (ABIN306633) specifically detects c-MYC. The antibody is reactive with Human, Mouse and Avian samples.

Quick Overview for c-MYC antibody (ABIN306633)

Target: c-MYC (MYC) (Myc Proto-Oncogene protein (MYC))

Reactivity: Human, Mouse, Avian

Host: Mouse

Clonality: Monoclonal

Conjugate: This c-MYC antibody is un-conjugated

Application: Please inquire

Clone: 4C6-1

Product Details anti-c-MYC Antibody

Isotype: IgG1

Application Details

Restrictions: For Research Use only

Handling

Target Details for c-MYC

Target: c-MYC (MYC) (Myc Proto-Oncogene protein (MYC))

Alternative Name: c-myc

Background: Human c-myc belongs to a family of 5 myc oncogenes. Amplification of c-myc has been found in several types of human tumors including breast and colon carcinomas. Induction of c-myc in cells grown in the appropriate growth factors or co-expression with survival genes, such as bcl-2 causes cell proliferation. In the abscence of these factors, c-myc expression causes cell death. c-myc gene gives rise to at least two nuclear phosphoproteins of 64kDa and 67kDa, the unphosphorylated form is 49kDa. Synonyms: cmyc, Myc proto-oncogene protein, transcription factor p64.

UniProt: P01106

Pathways: p53 Signaling, Cell Division Cycle, Sensory Perception of Sound, Transition Metal Ion Homeostasis, Mitotic G1-G1/S Phases, Positive Regulation of Endopeptidase Activity, Regulation of Carbohydrate Metabolic Process, Positive Regulation of Response to DNA Damage Stimulus, Warburg Effect