NPY5R antibody

Catalog No. ABIN317759

Product Details anti-NPY5R Antibody

Target: NPY5R (Neuropeptide Y Receptor Y5 (NPY5R))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NPY5R antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Specificity: NPY5-R antibody detects endogenous levels of NPY5-R protein.(region surrounding Met264)

Purification: Affinity Chromatography using epitope-specific immunogen.

Application Details

Application Notes: ELISA: 1/20000-1/40000. Western Blot: 1/500-1/1000. Immunofluorescence: 1/50-1/200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: Phosphate buffered saline (PBS), pH ~7.2 containing 0.05 % Sodium Azide as preservative.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for NPY5R

Target: NPY5R (Neuropeptide Y Receptor Y5 (NPY5R))

Alternative Name: NPY Receptor 5 / NPY5R (NPY5R Products)

Synonyms: NPY5-R antibody, NPYR5 antibody, NPYY5-R antibody, Y5R antibody, NPY5 antibody, MGC146705 antibody, NPY5R antibody, neuropeptide Y receptor Y5 antibody, neuropeptide Y receptor type 5 antibody, NPY5R antibody, Npy5r antibody, npy5r antibody, LOC786150 antibody

Background: Pancreatic polypeptide (PP), neuropeptide Y (NPY), and peptide YY (PYY) are related 36-amino acid hormones. A number of structurally related receptors for these peptides have been isolated, NPY1-R, NPY2-R, NPY3-R, NPY4-R, NPY5-R, and NPY6-R. NPY4-R is expressed in several human tissues, including brain, coronary artery, and ileum. NPY4-R maps to human chromosome 10q11.2-q21.2. NPY-5R, isolated from rat hypothalamus, encodes a 456-amino acid protein with less than 35 % overall identity to known Y-type receptors. The human NPY-5R sequence is nearly identical to, but in the opposite orientation from, that of the human NPY-1R sequence. NPY5-R localizes to the paraventricular hypothalamic nucleus, the lateral hypothalamus, and other locations consistent with a role in the control of feeding behavior. The gene which encodes NPY-5R maps to human chromosome 4q31-32. NPY-6R is abundantly expressed in human heart and skeletal muscle and the gene which encodes NPY-6R maps to human chromosome 5q31.Synonyms: NPY-Y5 receptor, NPY5-R, NPYR5, NPYY5, Neuropeptide Y receptor 5

Molecular Weight: approx. 48 kDa

Gene ID: 4889

NCBI Accession: NP_006165

UniProt: Q15761

Pathways: Feeding Behaviour