ELISA: 1/5000-1/10000. Western Blot: 1/500-1/1000. Immunohistochemistry: 1/50-1/200. Immunoprecipitation: 1/50-1/200. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
SLEB11 antibody, signal transducer and activator of transcription 4 antibody, STAT4 antibody, stat4 antibody, Stat4 antibody
Background
Drosophila melanogaster is a proven and effective model for studying developmental and cellular processes common to higher eukaryotes. Approximately 13,600 genes have been elucidated from more than 120 megabases of euchromatin, and they are organized among the chromosomes 2, 3, 4, X and Y, with the Y chromosome being predominately heterochromatic. Drosophila genes can be categorized based on the type of protein for which they encode and are represented by six major classifications, which include intracellular signaling proteins, transmembrane proteins, RNA binding proteins, secreted factors, transcription regulators (basic helix-loop-helix, homeodomain containing, zinc finger containing, and chromatin associated) or other functional proteins. Many of the genes expressed in Drosophila are structurally and functionally similar across species, as are the pathways involved in transducing intracellular signaling. Marelle (Stat, Signal-transducer and activator of transcription protein) is an SH2 domain-containing, invertebrate homolog of the mammalian Stat transcription factor.Synonyms: Signal transducer and activator of transcription 4