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SUMO1 antibody (N-Term)
SUMO1
Reactivity: Human, Rat, Mouse
WB, IF
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-SUMO1 Antibody
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Target
See all SUMO1 Antibodies
SUMO1
(Small Ubiquitin Related Modifier Protein 1 (SUMO1))
Binding Specificity
All epitopes for SUMO1 antibodies
N-Term
Reactivity
All reactivities for SUMO1 antibodies
Human, Rat, Mouse
Host
All hosts for SUMO1 antibodies
Rabbit
Clonality
All clonalities for SUMO1 antibodies
Polyclonal
Conjugate
All conjugates for SUMO1 antibodies
This SUMO1 antibody is un-conjugated
Application
All applications for SUMO1 antibodies
Western Blotting (WB), Immunofluorescence (IF)
Specificity
This antibody detects an epitope within the N-terminal (NT) region of small ubiquitin-related modifier-1 (SUMO-1).
Purification
Purified
Immunogen
14 amino acid peptide sequence near the amino terminus of human SUMO-1
Isotype
IgG
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Discover our top product SUMO1 Primary Antibody
Alternatives
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Application Details
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Application Notes
Western blot: 0.5 - 1.0 μg/mL, detects a band of approximately 15 kDa in HL60 cell lysates. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions
For Research Use only
Handling
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Concentration
1.0 mg/mL
Buffer
Phosphate buffered saline containing 0.02 % Sodium Azide
Preservative
Sodium azide
Precaution of Use
This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Handling Advice
Avoid repeated freezing and thawing.
Storage
4 °C/-20 °C
Storage Comment
Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Target Details for SUMO1
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Target
SUMO1
(Small Ubiquitin Related Modifier Protein 1 (SUMO1))
Alternative Name
SUMO1 (SUMO1 Products )
Synonyms
DAP1 antibody, GMP1 antibody, OFC10 antibody, PIC1 antibody, SENP2 antibody, SMT3 antibody, SMT3C antibody, SMT3H3 antibody, UBL1 antibody, hm:zeh0670 antibody, wu:fb74c02 antibody, wu:fd12c02 antibody, zgc:65934 antibody, zgc:85634 antibody, SUMO1 antibody, dap1 antibody, gmp1 antibody, ofc10 antibody, pic1 antibody, senp2 antibody, smt3 antibody, smt3c antibody, sumo-1 antibody, sumo1 antibody, ubl1 antibody, xsumo-1 antibody, xsumo1 antibody, ARABIDOPSIS THALIANA SMALL UBIQUITIN-LIKE MODIFIER 1 antibody, ATSUMO1 antibody, F10M23.180 antibody, F10M23_180 antibody, SMALL UBIQUITIN-LIKE MODIFIER 1 antibody, SUM1 antibody, SUMO 1 antibody, small ubiquitin-like modifier 1 antibody, pigSUMO1 antibody, SENTRIN antibody, SMTP3 antibody, SUMO-1 antibody, Smt3C antibody, Ubl1 antibody, small ubiquitin-like modifier 1 antibody, small ubiquitin-like modifier 1 S homeolog antibody, small ubiquitin-related protein 1 antibody, SMT3 suppressor of mif two 3 homolog 1 (S. cerevisiae) antibody, SMT3 suppressor of mif two 3 homolog 1 (yeast) antibody, small ubiquitin-like modifier 1 L homeolog antibody, Sumo1 antibody, SUMO1 antibody, sumo1 antibody, sumo1.S antibody, sumo-1 antibody, sumo1.L antibody
Background
SUMO-1 is an 11kD protein which structurally related to ubiquitin, and is added to proteins as a form of post-translational modification known as sumoylation. Sumoylation can be cell cycle regulated, stimulated upon stress or induced by DNA damage, and binding elicits individual effects for each protein. Effects include changes to protein stability, nuclear-cytosolic transport, and transcriptional regulation (mostly transcriptional repression). Alternate transcriptional splice variants encoding different isoforms have been characterized.Synonyms: GAP-modifying protein 1, GMP1, SMT3 homolog 3, SMT3C, SMT3H3, Sentrin, Small ubiquitin-related modifier 1, UBL1, Ubiquitin-homology domain protein PIC1, Ubiquitin-like protein SMT3C, Ubiquitin-like protein UBL1
Gene ID
7341
NCBI Accession
NP_001005781
UniProt
P63165
Pathways
M Phase , Positive Regulation of Endopeptidase Activity , Protein targeting to Nucleus , Ubiquitin Proteasome Pathway
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