Prostate Specific Antigen antibody

Catalog No. ABIN356465

The Rabbit Polyclonal anti-Prostate Specific Antigen antibody is suitable to detect Prostate Specific Antigen in samples from Human. It has been validated for IF, IHC (p) and IHC (fro).

Quick Overview for Prostate Specific Antigen antibody (ABIN356465)

Target: Prostate Specific Antigen (PSA)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Prostate Specific Antigen antibody is un-conjugated

Application: Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-Prostate Specific Antigen Antibody

Specificity: This antibody reacts with prostate ductal epithelium in both normal and malignant prostate tissue.
Cellular Localization: Cytoplasmic.

Purification: Protein A Chromatography.

Immunogen: Purified human PSA.

Isotype: IgG

Application Details

Application Notes: Suitable for Immunohistochemistry and Immunocytochemistry (Frozen or Formalin-FixedParaffin-Embedded (FFPE) tissue sections and cell smears). For IHC dilute concentared antibody at 1/50-1/100 using streptavidinapprox. biotin system orpolymer system. Immunofluorescence. Recommended Positive Control: Human normal or malignant prostate tissue.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 2.0 mg/mL

Buffer: PBS, pH 7.4 containing 1 % BSA as stabilizer and 0.05 % Sodium Azide as preservative.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Target Details for Prostate Specific Antigen

Target: Prostate Specific Antigen (PSA)

Alternative Name: Kallikrein-3 / PSA / KLK3

Background: Prostate specific antigen (PSA) is a protein produced by the cells of the prostate gland. PSA is present in small quantities in the serum of normal men, and is often elevated in the presence of prostate cancer and in other prostate disorders. A blood test to measure PSA is the most effective test currently available for the early detection of prostate cancer. Higher than normal levels of PSA are associated with both localized and metastatic prostate cancer Prostate specific antigen (PSA), also known as is a 34 kDa glycoprotein manufactured almost exclusively by the prostate gland. Biochemically it is a serine protease enzyme (kallikrenin family), the gene of which is located on the nineteenth chromosome (19q13).Synonyms: Gamma-seminoprotein, P-30 antigen, Prostate-specific antigen, Semenogelase

Gene ID: 354

NCBI Accession: NP_001025218

UniProt: P07288

Pathways: Complement System