ZAP70 antibody

Catalog No. ABIN375389

The Rat Monoclonal anti-ZAP70 antibody has been validated for . It is suitable to detect ZAP70 in samples from Human.

Quick Overview for ZAP70 antibody (ABIN375389)

Target: ZAP70 (zeta-Chain (TCR) Associated Protein Kinase 70kDa (ZAP70))

Reactivity: Human

Host: Rat

Clonality: Monoclonal

Conjugate: This ZAP70 antibody is un-conjugated

Application: Please inquire

Product Details anti-ZAP70 Antibody

Characteristics: The antibody detects: Human TCR, Zap-70 (Mr 70 kDa)

To insure lot-to-lot consistency, each batch of product is tested by ELISA and/or PCFIA assay to conform to the characteristics of a standard reference reagent.

Purification: Purified

Isotype: IgG1

Application Details

Application Notes: Working Dilution:
<= 1 µg/10^6 cells
Representative data are included in this product insert.

Each laboratory should determine an optimum working titer for use in its particular application. Other applications have not been tested but use in such assays should not necessarily be excluded.

Restrictions: For Research Use only

Handling

Format: Liquid

Handling Advice: Each reagent is stable for the period shown on the bottle label if stored as directed.

Storage: 4 °C

Target Details for ZAP70

Target: ZAP70 (zeta-Chain (TCR) Associated Protein Kinase 70kDa (ZAP70))

Alternative Name: ZAP-70

Background: ZAP 70, also known as TCR associated protein, is a protein tyrosine kinase (PTK) with the primary role of catalyzing the phosphorylation of tyrosine residues in cellular proteins, and thus, contributes significantly to the initiation of cell signaling. ZAP 70 is expressed on T cells and NK cells. The monoclonal antibodies SB70 and SBZAP were generated against a KLH-peptide sequence corresponding to the human ZAP 70 amino acid residues 280-309.

Pathways: TCR Signaling, Ubiquitin Proteasome Pathway