CD46 antibody

Catalog No. ABIN379988

Product Details anti-CD46 Antibody

Target: CD46

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD46 antibody is un-conjugated

Application: Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Specificity: The antigen is CD46, the epitope is localized in the first two short consensus repeats. Antigen distribution: Isolated cells: The antigen is widely expressed on human cells except erythrocytes. It can also be found as a soluble protein in serum and saliva. Many human cell lines express CD46, e.g. U937, HeLa. Specificity: Human: CD46. Other species: positive in African green monkey, other species not tested.

Purification: Affinity purified

Immunogen: human U-251 cells

Clone: 13-42

Isotype: IgG1

Application Details

Application Notes: Approved: IHC, IHC-Fr (1:50), IHC-P (1:200 - 1:400)

Usage: For IHC-P, Proteinase K pretreatment for antigen retrieval is recommended.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Distilled Water.

Concentration: Lot specific

Buffer: Lyophilized from PBS  pH 7.2, 10 mg/mL BSA, 0.1 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid freeze-thaw cycles.

Storage: 4 °C,-20 °C

Storage Comment: Prior to reconstitution, 4°C. Following reconstitution store at -20°C. Avoid freeze-thaw cycles.

Target Details for CD46

Target: CD46

Alternative Name: MCP / CD46 (CD46 Products)

Synonyms: AHUS2 antibody, MCP antibody, MIC10 antibody, TLX antibody, TRA2.10 antibody, Mcp antibody, CD46 antibody, CD46 molecule antibody, CD46 antigen, complement regulatory protein antibody, CD46 molecule, complement regulatory protein antibody, membrane cofactor protein-like antibody, CD46 antibody, Cd46 antibody, LOC100341359 antibody, LOC103789310 antibody

Background: Name/Gene ID: CD46

Synonyms: CD46, AHUS2, CD46 antigen, MCP, Measles virus receptor, TLX, MIC10, TRA2.10, Membrane cofactor protein

Gene ID: 4179

UniProt: P15529

Pathways: Regulation of Actin Filament Polymerization