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USP8 antibody (C-Term)

USP8 Reactivity: Human WB, IHC (p) Host: Rabbit Polyclonal RB04288 unconjugated
Catalog No. ABIN388891
  • Target See all USP8 Antibodies
    USP8 (Ubiquitin Specific Peptidase 8 (USP8))
    Binding Specificity
    • 8
    • 6
    • 4
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1058-1087, C-Term
    Reactivity
    • 35
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 32
    • 2
    • 1
    Rabbit
    Clonality
    • 33
    • 2
    Polyclonal
    Conjugate
    • 25
    • 2
    • 2
    • 2
    • 2
    • 2
    This USP8 antibody is un-conjugated
    Application
    • 31
    • 15
    • 13
    • 6
    • 6
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Predicted Reactivity
    M
    Purification
    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
    Immunogen
    This USP8 (UBPY) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1058-1087 amino acids from the C-terminal region of human USP8 (UBPY).
    Clone
    RB04288
    Isotype
    Ig Fraction
    Top Product
    Discover our top product USP8 Primary Antibody
  • Application Notes
    WB: 1:1000. IHC-P: 1:50~100
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    Expiry Date
    6 months
  • Target
    USP8 (Ubiquitin Specific Peptidase 8 (USP8))
    Alternative Name
    USP8 (UBPY) (USP8 Products)
    Synonyms
    HumORF8 antibody, UBPY antibody, AI574262 antibody, AW557536 antibody, Ubpy antibody, mKIAA0055 antibody, ubiquitin carboxyl-terminal hydrolase 8 antibody, ubiquitin specific peptidase 8 antibody, LOC9310109 antibody, MGYG_00369 antibody, USP8 antibody, Usp8 antibody
    Background
    USP8 is a ubiquitin specific protease that plays an important regulatory role at the level of protein turnover by preventing degradation. USP8 is involved in cell proliferation, and probably regulates the stability of STAM2 and RASGRF1. USP8 may regulate T-cell anergy mediated by RNF128 via the formation of a complex containing RNF128 and STAM2. As revealed by structur/function studies, USP8 forms a ternary complex with RNF128 and OTUB1, and interacts with the SH3 domain of STAM2 and RASGRF1. Expression of USP8 is induced Upon growth stimulation in starved human fibroblasts, and expression decreases in response to growth arrest induced by cell-cell contact.
    Molecular Weight
    127523
    Gene ID
    9101
    NCBI Accession
    NP_001122082, NP_001122083, NP_005145
    UniProt
    P40818
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