This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogen
This NUR77(NR4A1) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 329-358 amino acids from human NUR77(NR4A1).
Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
4 °C,-20 °C
Storage Comment
Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date
6 months
Geradts, Groth, Wu, Jin: "Validation of an oligo-gene signature for the prognostic stratification of ductal carcinoma in situ (DCIS)." in: Breast cancer research and treatment, Vol. 157, Issue 3, pp. 447-59, (2017) (PubMed).
Target
NR4A1
(Nuclear Receptor Subfamily 4, Group A, Member 1 (NR4A1))
GFRP1 antibody, HMR antibody, N10 antibody, NAK-1 antibody, NGFIB antibody, NP10 antibody, NUR77 antibody, TR3 antibody, NGFI-B antibody, Gfrp antibody, Hbr-1 antibody, Hbr1 antibody, Hmr antibody, TIS1 antibody, nur77 antibody, Ngfi-b antibody, Nur77 antibody, nuclear receptor subfamily 4 group A member 1 antibody, nuclear receptor subfamily 4, group A, member 1 antibody, NR4A1 antibody, Nr4a1 antibody
Background
NR4A1 is a member of the steroid-thyroid hormone-retinoid receptor superfamily. Expression is induced by phytohemagglutinin in human lymphocytes and by serum stimulation of arrested fibroblasts. This protein acts as a nuclear transcription factor. Translocation of the protein from the nucleus to mitochondria induces apoptosis.