c-Rel antibody (Ser503)

Catalog No. ABIN401614

Product Details anti-c-Rel Antibody

Target: c-Rel (REL proto-oncogene (c-Rel))

Binding Specificity: Ser503

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This c-Rel antibody is un-conjugated

Application: Immunofluorescence (IF)

Specificity: Rel Antibody detects endogenous levels of total Rel protein.

Purification: Affinity chromatography

Immunogen: Synthesized non-phosphopeptide derived from human Rel around the phosphorylation site of serine 503 (T-S-SP-D-S)

Application Details

Application Notes: Immunofluorescence: 1/100 - 1/200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Buffer: Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: -20 °C

Target Details for c-Rel

Target: c-Rel (REL proto-oncogene (c-Rel))

Alternative Name: REL (c-Rel Products)

Synonyms: C-Rel antibody, c-Rel antibody, NFkB antibody, c-rel antibody, zgc:100833 antibody, Xrel2 antibody, Xrel3 antibody, rel antibody, rel-A antibody, rel2 antibody, rel3 antibody, v-rel antibody, xrel antibody, REL proto-oncogene, NF-kB subunit antibody, reticuloendotheliosis oncogene antibody, RELA proto-oncogene, NF-kB subunit antibody, v-rel avian reticuloendotheliosis viral oncogene homolog antibody, v-rel avian reticuloendotheliosis viral oncogene homolog L homeolog antibody, ribonuclease A family member 2 pseudogene antibody, REL antibody, Rel antibody, Rela antibody, rel antibody, rel.L antibody, ECRP antibody

Background: C-Rel is the cellular cognate of v-Rel, the avian reticuloendo-theliosis virus strain T transforming gene. V-Rel encodes a 59 kDa phosphoprotein that is located in the cytoplasm of transformed spleen cells and in the nucleus of non-transformed fibroblasts, in contrast to the c-Rel protein which is cytoplasmic. C-Rel was shown to represent a constituent of the kB site binding transcription factor NFkB, which plays a crucial role in the expression of immunoglobulin k light chain gene.Synonyms: C-Rel proto-oncogene protein, c-Rel

Gene ID: 5966

NCBI Accession: NP_002899

UniProt: Q04864