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Integrin Alpha2b antibody

CD41 Reactivity: Human FACS, IHC (fro), IF, IP, ICC Host: Mouse Monoclonal M148 unconjugated

Catalog No. ABIN4880137

Datasheet as PDF

Target See all Integrin Alpha2b (CD41) Antibodies

Integrin Alpha2b (CD41)
Reactivity
107

29

21

5

5

4

3

2

2

2

1

1

1

1

1
Human
Host
66

43

20
Mouse
Compatible Secondaries
Clonality
83

40

1
Monoclonal
Conjugate
54

14

12

11

4

4

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
This Integrin Alpha2b antibody is un-conjugated
Application
93

42

25

25

19

17

13

13

10

8

8

4

3

1

1

1

1

1
Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunofluorescence (IF), Immunoprecipitation (IP), Immunocytochemistry (ICC)

Specificity

This antibody recognises integrin alpha 2b, a 110-130 kDa transmembrane protein that is also known as CD41. CD41 associates with the integrin CD61 to form the CD41/CD61 (GPIIb/IIIa) heterodimer, a fibronectin receptor expressed in platelets. The antibody M148 binds to some medulloblastoma and neuroblastoma cells and rhabdomyosarcoma and certain other solid tumours. No binding is observed to marrow constituents other than platelets and megakaryocytes. The antibody M148 prevents aggregation of platelets.

Purification

Purified on protein A from tissue culture supernatant.

Immunogen

Homogenized human medulloblastoma tissue.

Clone

M148

Isotype

IgG1

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anti-Integrin Alpha2b (CD41) (Internal Region) antibody
CD41 Reactivity: Human WB, IHC (p) Host: Rabbit Polyclonal unconjugated

anti-Integrin Alpha2b (CD41) antibody
CD41 Reactivity: Mouse FACS, ELISA, IHC (fro), IP, IHC (p), Func Host: Rat Monoclonal MWReg30 unconjugated

anti-Integrin Alpha2b (CD41) antibody
CD41 Reactivity: Mouse FACS, ELISA, IHC (fro), IP, IHC (p) Host: Rat Monoclonal MWReg30 unconjugated

anti-Integrin Alpha2b (CD41) antibody
CD41 Reactivity: Human, Non-Human Primate FACS, IHC (fro) Host: Mouse Monoclonal HIP2 unconjugated

anti-Integrin Alpha2b (CD41) antibody (Biotin)
CD41 Reactivity: Human FACS Host: Mouse Monoclonal MEM-06 Biotin

anti-Integrin Alpha2b (CD41) antibody (FITC)
CD41 Reactivity: Human FACS Host: Mouse Monoclonal MEM-06 FITC

anti-Integrin Alpha2b (CD41) (AA 677-711), (C-Term) antibody
CD41 Reactivity: Human, Mouse, Rat WB, IHC (p) Host: Rabbit Polyclonal unconjugated

anti-Integrin Alpha2b (CD41) (AA 639-887) antibody
CD41 Reactivity: Human ELISA, IHC, IF Host: Rabbit Polyclonal unconjugated

Application Notes

Optimal antibody dilution should be determined by titration

Comment

Myeloma, fusion partners: Cells from immunized Balb/c mice were fused with the P3X63Ag8.653 myeloma cell line

Restrictions

For Research Use only
Format

Liquid

Concentration

1 mg/mL

Buffer

Purified IgG supplied in Phosphate buffered saline (PBS) containing 0.09 % Sodium azide

Preservative

Sodium azide

Precaution of Use

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Target

Integrin Alpha2b (CD41)

Alternative Name

CD41 (CD41 Products)

Synonyms

AI172977 antibody, CD41 antibody, CD41B antibody, GpIIb antibody, alphaIIb antibody, BDPLT16 antibody, BDPLT2 antibody, GP2B antibody, GPIIb antibody, GT antibody, GTA antibody, HPA3 antibody, integrin alpha 2b antibody, integrin subunit alpha 2b antibody, Itga2b antibody, ITGA2B antibody

Gene ID

3689

OMIM

607759

UniProt

P20701

Pathways

Integrin Complex