DUOX1 antibody

Catalog No. ABIN4903524

Product Details anti-DUOX1 Antibody

Target: DUOX1 (Dual Oxidase 1 (DUOX1))

Reactivity: Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DUOX1 antibody is un-conjugated

Application: Western Blotting (WB)

Characteristics: The protein encoded by this gene is a glycoprotein and a member of the NADPH oxidase family. The synthesis of thyroid hormone is catalyzed by a protein complex located at the apical membrane of thyroid follicular cells. This complex contains an iodide transporter, thyroperoxidase, and a peroxide generating system that includes proteins encoded by this gene and the similar DUOX2 gene. This protein is known as dual oxidase because it has both a peroxidase homology domain and a gp91phox domain. This protein generates hydrogen peroxide and thereby plays a role in the activity of thyroid peroxidase, lactoperoxidase, and in lactoperoxidase-mediated antimicrobial defense at mucosal surfaces. Two alternatively spliced transcript variants encoding the same protein have been described for this gene.

Purification: Affinity purification

Immunogen: Recombinant protein of human DUOX1.

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.4

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze/thaw cycles.

Storage: -20 °C

Storage Comment: Store at -20°C.

Target Details for DUOX1

Target: DUOX1 (Dual Oxidase 1 (DUOX1))

Alternative Name: DUOX1 (DUOX1 Products)

Synonyms: Udx1 antibody, duox1 antibody, LNOX1 antibody, NOXEF1 antibody, THOX1 antibody, 9930101G15Rik antibody, AW987690 antibody, Duox2 antibody, LNOX2 antibody, NOXEF2 antibody, P138-TOX antibody, THOX2 antibody, dual oxidase 1 antibody, dual oxidase antibody, duox1 antibody, DUOX1 antibody, duox antibody, LOC5569378 antibody, Duox1 antibody

Gene ID: 53905

UniProt: Q9NRD9