×
For best experience we recommend to activate Javascript in your browser.
JNK antibody
MAPK8
Reactivity: Human, Mouse, Rat
WB, IHC, IF, FACS, IP, ICC
Host: Rabbit
Monoclonal
unconjugated
Product Details anti-JNK Antibody
(hide)
Target
See all JNK (MAPK8) Antibodies
JNK (MAPK8)
(Mitogen-Activated Protein Kinase 8 (MAPK8))
Reactivity
All reactivities for JNK antibodies
Human, Mouse, Rat
Host
All hosts for JNK antibodies
Rabbit
Clonality
All clonalities for JNK antibodies
Monoclonal
Conjugate
All conjugates for JNK antibodies
This JNK antibody is un-conjugated
Application
All applications for JNK antibodies
Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS), Immunoprecipitation (IP), Immunocytochemistry (ICC)
Characteristics
The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is activated by various cell stimuli, and targets specific transcription factors, and thus mediates immediate-early gene expression in response to cell stimuli. The activation of this kinase by tumor-necrosis factor alpha (TNF-alpha) is found to be required for TNF-alpha induced apoptosis. This kinase is also involved in UV radiation induced apoptosis, which is thought to be related to cytochrom c-mediated cell death pathway. Studies of the mouse counterpart of this gene suggested that this kinase play a key role in T cell proliferation, apoptosis and differentiation. Several alternatively spliced transcript variants encoding distinct isoforms have been reported.
Purification
Affinity purification
Immunogen
A phospho specific peptide corresponding to residues surrounding T183/T183/T221 of human JNK1/2/3.
Isotype
IgG
Top Product
Discover our top product MAPK8 Primary Antibody
Alternatives
(show)
anti-Mitogen-Activated Protein Kinase 8 (MAPK8) (pThr183), (pTyr185) antibody
MAPK8
Reactivity: Human, Mouse, Rat, Dog, Rabbit
WB, ELISA, IHC (p), FACS, IF (cc), IF (p), ICC, IHC (fro)
Host: Rabbit
Polyclonal
unconjugated
anti-Mitogen-Activated Protein Kinase 8 (MAPK8) (AA 201-300) antibody
MAPK8
Reactivity: Human, Mouse, Rat, Chicken, Dog
WB, ELISA, IHC (p), FACS, IF (cc), IF (p), IHC (fro)
Host: Rabbit
Polyclonal
unconjugated
Application Details
(hide)
Application Notes
WB 1:500-1:2000 , IHC 1:50-1:200 , ICC 1:50-1:200 , IF 1:50-1:100 , IP 1:20-1:50 , FC 1:20-1:50
Restrictions
For Research Use only
Handling
(hide)
Format
Liquid
Concentration
1 mg/mL
Buffer
PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.4
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
Avoid repeated freeze/thaw cycles.
Storage
-20 °C
Storage Comment
Store at -20°C.
Target Details for JNK
(hide)
Target
JNK (MAPK8)
(Mitogen-Activated Protein Kinase 8 (MAPK8))
Alternative Name
JNK1/2/3 (MAPK8 Products )
Synonyms
JNK antibody, JNK-46 antibody, JNK1 antibody, JNK1A2 antibody, JNK21B1/2 antibody, PRKM8 antibody, SAPK1 antibody, SAPK1c antibody, AI849689 antibody, Prkm8 antibody, BSK antibody, BSK/DJNK antibody, Bsk antibody, CG5680 antibody, D-JNK antibody, D-junk antibody, DBSK/JNK antibody, DJNK antibody, DJNK/bsk antibody, Dmel\\CG5680 antibody, JNK/SAPK antibody, Jnk antibody, Junk antibody, SAPKa antibody, c-Jun antibody, dJNK antibody, jnk antibody, T10F20.15 antibody, jnk1 antibody, sapk1 antibody, mapk8 antibody, zgc:112379 antibody, JNKb antibody, mapk8b antibody, mitogen-activated protein kinase 8 antibody, Stress-activated protein kinase jnk-1 antibody, basket antibody, Protein kinase superfamily protein antibody, mitogen-activated protein kinase 8 L homeolog antibody, mitogen-activated protein kinase 8b antibody, mitogen-activated protein kinase 8B-like antibody, MAPK8 antibody, jnk-1 antibody, Mapk8 antibody, bsk antibody, ATMPK8 antibody, mapk8.L antibody, mapk8b antibody, LOC109094263 antibody
Gene ID
5599, 5601, 5602
UniProt
P45983 , P45984 , P53779
Pathways
MAPK Signaling , WNT Signaling , TLR Signaling , Fc-epsilon Receptor Signaling Pathway , Neurotrophin Signaling Pathway , Activation of Innate immune Response , Hepatitis C , Toll-Like Receptors Cascades , Signaling of Hepatocyte Growth Factor Receptor , S100 Proteins
Recently viewed
(hide)