Tyrosine Hydroxylase antibody (AA 513-524)

Catalog No. ABIN490419

Product Details anti-Tyrosine Hydroxylase Antibody

Target: Tyrosine Hydroxylase (TH)

Binding Specificity: AA 513-524

Reactivity: Human

Host: Goat

Clonality: Polyclonal

Conjugate: This Tyrosine Hydroxylase antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Specificity: Human TH / Tyrosine Hydroxylase. This antibody is expected to recognise all three reported isoforms (as represented by NP_954986.2, NP_000351.2, NP_954987.2).

Predicted Reactivity: Percent identity by BLAST analysis: Human, Gorilla, Baboon, Monkey (100%) Marmoset, Rat, Hamster, Dog, Pig (92%) Bat, Rabbit (83%).

Purification: Immunoaffinity purified

Immunogen: Synthetic peptide C-VQDELDTLAHAL from the C-terminus of human TH / Tyrosine Hydroxylase (NP_954986.2, NP_000351.2, NP_954987.2). Percent identity by BLAST analysis: Human, Gorilla, Baboon, Monkey (100%), Marmoset, Rat, Hamster, Dog, Pig (92%), Bat, Rabbit (83%).

Type of Immunogen: Synthetic peptide

Application Details

Application Notes: Approved: Peptide-ELISA (1:8000), WB (2 - 4 μg/mL)

Usage: Peptide ELISA: antibody detection limit dilution 1:8000. Western blot: Approx 55  kDa band observed in Human Brain (Cerebral Cortex) lysates (calculated MW of 55.5  kDa according to NP_000351.2). Recommended concentration: 2-4 μg/mL.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Tris-buffered saline,  pH 7.3, 0.5 % BSA, 0.02 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Minimize freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze-thaw cycles.

Target Details for Tyrosine Hydroxylase

Target: Tyrosine Hydroxylase (TH)

Alternative Name: TH / Tyrosine Hydroxylase (TH Products)

Synonyms: DYT14 antibody, DYT5b antibody, TYH antibody, The antibody, CG10118 antibody, DH65B antibody, DTH antibody, Dmel\\CG10118 antibody, Pale antibody, Ple antibody, TH antibody, Th antibody, VII antibody, dTH1 antibody, dTH65B antibody, pale/ple antibody, th antibody, dyt14 antibody, dyt5b antibody, tyh antibody, tyrosine hydroxylase antibody, pale antibody, tyrosine 3-monooxygenase antibody, tyrosine hydroxylase S homeolog antibody, TH antibody, Th antibody, ple antibody, th antibody, th.S antibody, LOC100008895 antibody

Background: Name/Gene ID: TH
Family: Monooxygenase

Synonyms: TH, DYT14, Dystonia 14, TYH, Tyrosine 3-hydroxylase, Tyrosine hydroxylase, DYT5b, Tyrosine 3-monooxygenase

Gene ID: 7054

NCBI Accession: NP_954986, NP_000351, NP_954987

UniProt: P07101

Pathways: Dopaminergic Neurogenesis, Response to Water Deprivation, Sensory Perception of Sound, Carbohydrate Homeostasis, Feeding Behaviour