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NFKBIA antibody
NFKBIA
Reactivity: Human
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-NFKBIA Antibody
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Target
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NFKBIA
(Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B-Cells Inhibitor, alpha (NFKBIA))
Reactivity
All reactivities for NFKBIA antibodies
Human
Host
All hosts for NFKBIA antibodies
Rabbit
Clonality
All clonalities for NFKBIA antibodies
Polyclonal
Conjugate
All conjugates for NFKBIA antibodies
This NFKBIA antibody is un-conjugated
Application
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Characteristics
The NF-κB/Rel transcription factors are present in the cytosol in an inactive state complexed with the inhibitory IκB proteins (1-3). Activation occurs via phosphorylation of IκBα at Ser32 and Ser36 followed by proteasome-mediated degradation that results in the release and nuclear translocation of active NF-κB (3-7). IκBα phosphorylation and resulting Rel-dependent transcription are activated by a highly diverse group of extracellular signals including inflammatory cytokines, growth factors, and chemokines. Kinases that phosphorylate IκB at these activating sites have been identified (8).
Purification
Affinity purification
Immunogen
Recombinant protein of human NFKBIA.
Isotype
IgG
Top Product
Discover our top product NFKBIA Primary Antibody
Alternatives
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anti-Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B-Cells Inhibitor, alpha (NFKBIA) (AA 1-120) antibody
NFKBIA
Reactivity: Human, Mouse, Rat, Cow, Chicken
WB, ELISA, IHC (p), IF (cc), IF (p), FACS, IHC (fro)
Host: Rabbit
Polyclonal
unconjugated
Application Details
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Application Notes
WB 1:500-1:2000 , IF 1:20-1:100
Restrictions
For Research Use only
Handling
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Format
Liquid
Concentration
1 mg/mL
Buffer
PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.4
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
Avoid repeated freeze/thaw cycles.
Storage
-20 °C
Storage Comment
Store at -20°C.
Target Details for NFKBIA
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Target
NFKBIA
(Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B-Cells Inhibitor, alpha (NFKBIA))
Alternative Name
NFKBIA (NFKBIA Products )
Synonyms
IKBA antibody, MAD-3 antibody, NFKBI antibody, AI462015 antibody, Nfkbi antibody, RL/IF-1 antibody, ECI-6/IKBA antibody, NFKBIA antibody, ikbaB antibody, wu:fb81f08 antibody, zgc:56666 antibody, zgc:77616 antibody, ikbaA antibody, wu:fj16a07 antibody, zgc:85769 antibody, NFKB inhibitor alpha antibody, nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, alpha antibody, nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha b antibody, nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha a antibody, NFKBIA antibody, Nfkbia antibody, nfkbiab antibody, nfkbiaa antibody
Gene ID
4792
UniProt
P25963
Pathways
NF-kappaB Signaling , TCR Signaling , TLR Signaling , Fc-epsilon Receptor Signaling Pathway , Activation of Innate immune Response , Cellular Response to Molecule of Bacterial Origin , Maintenance of Protein Location , Hepatitis C , Protein targeting to Nucleus , Toll-Like Receptors Cascades , BCR Signaling
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