EPHA1 antibody (AA 29-60)

Catalog No. ABIN3030830

Product Details anti-EPHA1 Antibody

Target: EPHA1 (Ephrin Type A Receptor 1 (EPHA1))

Binding Specificity: AA 29-60

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This EPHA1 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS)

Purification: Purified

Immunogen: A portion of amino acids 29-60 from the human protein was used as the immunogen for this EphA1 antibody.

Isotype: Ig Fraction

Application Details

Application Notes: Titration of the EphA1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. IHC (Paraffin): 1:50-1:100,Flow Cytometry: 1:10-1:50

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the EphA1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Target Details for EPHA1

Target: EPHA1 (Ephrin Type A Receptor 1 (EPHA1))

Alternative Name: EphA1 (EPHA1 Products)

Synonyms: EPH antibody, EPHT antibody, EPHT1 antibody, 5730453L17Rik antibody, AL033318 antibody, Eph antibody, Esk antibody, EPHA9 antibody, EPH receptor A1 antibody, Eph receptor A1 antibody, EPHA1 antibody, Epha1 antibody

Background: Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains. The tyrosine kinase (TK) group is mainly involved in the regulation of cell-cell interactions such as differentiation, adhesion, motility and death. There are currently about 90 TK genes sequenced, 58 are of receptor protein TK (e.g. EGFR, EPH, FGFR, PDGFR, TRK, and VEGFR families), and 32 of cytosolic TK (e.g. ABL, FAK, JAK, and SRC families).

UniProt: P21709