c-MET antibody (Catalytic Domain)
Quick Overview for c-MET antibody (Catalytic Domain) (ABIN3031757)
Target
See all c-MET (MET) AntibodiesReactivity
Host
Clonality
Conjugate
Application
Clone
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Binding Specificity
- Catalytic Domain
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Purpose
- MET Antibody (HGFR)
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Purification
- Purified
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Immunogen
- This MET antibody was produced from mice immunized with purified recombinant protein encoding the catalytic domain of human MET/HGFR.
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Isotype
- IgG1
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Application Notes
- Titration of the MET antibody (HGFR) may be required due to differences in protocols and secondary/substrate sensitivity.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- Aliquot the MET antibody (HGFR) and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- c-MET (MET) (Met Proto-Oncogene (MET))
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Alternative Name
- MET
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Background
- The proto-oncogene MET product is the hepatocyte growth factor receptor and encodes tyrosine-kinase activity. The primary single chain precursor protein is post-translationally cleaved to produce the alpha and beta subunits, which are disulfide linked to form the mature receptor. Various mutations in the MET gene are associated with papillary renal carcinoma. Two transcript variants encoding different isoforms have been found for this gene.
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UniProt
- P08581
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Pathways
- RTK Signaling, Carbohydrate Homeostasis, Synaptic Membrane, Signaling of Hepatocyte Growth Factor Receptor
Target
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