FMR1 antibody

Catalog No. ABIN5002774

Product Details anti-FMR1 Antibody

Target: FMR1 (Fragile X Mental Retardation 1 (FMR1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This FMR1 antibody is un-conjugated

Application: Western Blotting (WB)

Cross-Reactivity: Human

Purification: Mouse monoclonal antibody supplied in crude ascites with 0.09% (W/V) sodium azide.

Immunogen: This FMR1 antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 20-48 amino acids from human FMR1.

Clone: 8C2

Isotype: IgM

Application Details

Application Notes: WB 1:300-5000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for FMR1

Target: FMR1 (Fragile X Mental Retardation 1 (FMR1))

Alternative Name: FMR1 (FMR1 Products)

Synonyms: AT24755 antibody, BcDNA:GM08679 antibody, CG6203 antibody, Dmel\\CG6203 antibody, EP(3)3517 antibody, FMR antibody, FMR1 antibody, FMRP antibody, FMRp antibody, FXR antibody, Fmrp antibody, cg6203 antibody, dFMR antibody, dFMR1 antibody, dFMRP antibody, dFXR antibody, dFXR1 antibody, dFXRP antibody, dFmr1 antibody, dFmrp antibody, dfmr antibody, dfmr1 antibody, dfxr antibody, dfxr1 antibody, dmfr1 antibody, fmr antibody, fmr1 antibody, FRAXA antibody, POF antibody, POF1 antibody, zFMR1 antibody, Fmr-1 antibody, CG6203 gene product from transcript CG6203-RC antibody, fragile X mental retardation 1 antibody, fragile X mental retardation syndrome 1 antibody, Fmr1 antibody, FMR1 antibody, fmr1 antibody

Background:

Synonyms: POF, FMRP, POF1, FRAXA, Synaptic functional regulator FMR1, Fragile X mental retardation protein 1, Protein FMR-1, FMR1

Background: The protein encoded by this gene binds RNA and is associated with polysomes. The encoded protein may be involved in mRNA trafficking from the nucleus to the cytoplasm. A trinucleotide repeat (CGG) in the 5' UTR is normally found at 6-53 copies, but an expansion to 55-230 repeats is the cause of fragile X syndrome. Expansion of the trinucleotide repeat may also cause one form of premature ovarian failure (POF1). Multiple alternatively spliced transcript variants that encode different protein isoforms and which are located in different cellular locations have been described for this gene.

Gene ID: 2332

UniProt: Q06787

Pathways: Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development