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Leptin Receptor antibody (AA 901-1000) (AbBy Fluor® 750)

LEPR Reactivity: Human, Mouse, Rat, Pig WB, FACS, IF (p), IF (cc) Host: Rabbit Polyclonal AbBy Fluor® 750
Catalog No. ABIN5006146
  • Target See all Leptin Receptor (LEPR) Antibodies
    Leptin Receptor (LEPR)
    Binding Specificity
    • 16
    • 15
    • 10
    • 9
    • 7
    • 6
    • 5
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 901-1000
    Reactivity
    • 107
    • 70
    • 48
    • 18
    • 12
    • 4
    • 3
    • 3
    Human, Mouse, Rat, Pig
    Host
    • 110
    • 14
    • 2
    • 2
    • 1
    • 1
    Rabbit
    Clonality
    • 107
    • 23
    Polyclonal
    Conjugate
    • 49
    • 11
    • 7
    • 6
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    This Leptin Receptor antibody is conjugated to AbBy Fluor® 750
    Application
    • 81
    • 42
    • 35
    • 34
    • 25
    • 25
    • 16
    • 11
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc))
    Specificity
    This antibody will recognize the Isoform B variant only
    Cross-Reactivity
    Human, Mouse, Pig, Rat
    Predicted Reactivity
    Dog,Cow,Sheep
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human Leptin receptor:901-1000/1165
    Isotype
    IgG
    Top Product
    Discover our top product LEPR Primary Antibody
  • Application Notes
    FCM 1:20-100
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Expiry Date
    12 months
  • Target
    Leptin Receptor (LEPR)
    Alternative Name
    Leptin receptor (Isoform B) (LEPR Products)
    Synonyms
    CD295 antibody, LEP-R antibody, LEPRD antibody, OB-R antibody, OBR antibody, obr antibody, cd295 antibody, ob-rb antibody, Fa antibody, LEPROT antibody, Leprb antibody, Modb1 antibody, OB-RGRP antibody, Obr antibody, db antibody, diabetes antibody, obese-like antibody, obl antibody, ObRb antibody, Ob-R antibody, Ob-RM antibody, lepr antibody, leptin receptor antibody, leptin receptor S homeolog antibody, LEPR antibody, lepr antibody, Lepr antibody, lepr.S antibody
    Background

    Synonyms: OBR, OB-R, CD295, LEP-R, LEPRD, Leptin receptor, HuB219, OB receptor, LEPR, DB, LEPR_MOUSE

    Background: Receptor for obesity factor (leptin). On ligand binding, mediates signaling through JAK2/STAT3. Involved in the regulation of fat metabolism and, in a hematopoietic pathway, required for normal lymphopoiesis. May play a role in reproduction. Can also mediate the ERK/FOS signaling pathway (By similarity).

    Gene ID
    3953
    UniProt
    P48357
    Pathways
    JAK-STAT Signaling, AMPK Signaling, Feeding Behaviour
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