BCL6 antibody (AA 200-401)
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- Target See all BCL6 Antibodies
- BCL6 (B-Cell CLL/lymphoma 6 (BCL6))
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Binding Specificity
- AA 200-401
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Reactivity
- Human
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This BCL6 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Purification
- Protein G Chromatography
- Immunogen
- A partial length recombinant BCL-6 protein (amino acids 200-401) was used as the immunogen for this antibody.
- Clone
- ABM44G9
- Isotype
- IgG2b kappa
- Top Product
- Discover our top product BCL6 Primary Antibody
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anti-B-Cell CLL/lymphoma 6 (BCL6) (AA 501-600) antibody
BCL6 Reactivity: Human, Mouse WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) Host: Rabbit Polyclonal unconjugated
anti-B-Cell CLL/lymphoma 6 (BCL6) (Internal Region) antibodyBCL6 Reactivity: Human, Mouse, Rat WB, ELISA, IHC (p) Host: Rabbit Polyclonal unconjugated
anti-B-Cell CLL/lymphoma 6 (BCL6) (AA 147-276) antibodyBCL6 Reactivity: Human WB, ELISA, FACS, IHC, ICC, Neut Host: Mouse Monoclonal 2G1B6 unconjugated
anti-B-Cell CLL/lymphoma 6 (BCL6) (AA 256-389) antibodyBCL6 Reactivity: Human IHC, StM Host: Mouse Monoclonal BCL6-1527 unconjugated
anti-B-Cell CLL/lymphoma 6 (BCL6) (Internal Region) antibodyBCL6 Reactivity: Human, Mouse WB, IHC (p), IP, ChIP Host: Rabbit Polyclonal unconjugated
anti-B-Cell CLL/lymphoma 6 (BCL6) (Internal Region) antibodyBCL6 Reactivity: Human, Rat WB, ELISA, IHC, IF, ICC Host: Rabbit Polyclonal unconjugated
anti-B-Cell CLL/lymphoma 6 (BCL6) (AA 519-547) antibodyBCL6 Reactivity: Human, Mouse WB, ELISA, FACS, IHC Host: Rabbit Polyclonal unconjugated
anti-B-Cell CLL/lymphoma 6 (BCL6) (AA 519-547), (C-Term) antibodyBCL6 Reactivity: Human, Mouse WB, FACS, IHC (p) Host: Rabbit Polyclonal RB19464 unconjugated
anti-B-Cell CLL/lymphoma 6 (BCL6) (AA 256-389) antibodyBCL6 Reactivity: Human WB Host: Mouse Monoclonal BCL6-1475 unconjugated
anti-B-Cell CLL/lymphoma 6 (BCL6) (AA 256-389) antibodyBCL6 Reactivity: Human ELISA, IHC, StM, Coat Host: Mouse Monoclonal BCL6-1982 unconjugated
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- Application Notes
- WB: 2-4 μg/mL
- Restrictions
- For Research Use only
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- Concentration
- 0.5 mg/mL
- Buffer
- PBS containing 0.05 % BSA, PH 7.4
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C/-20 °C
- Storage Comment
- Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
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- Target
- BCL6 (B-Cell CLL/lymphoma 6 (BCL6))
- Alternative Name
- BCL-6 (BCL6 Products)
- Synonyms
- bcl5 antibody, laz3 antibody, bcl6a antibody, znf51 antibody, zbtb27 antibody, MGC132260 antibody, Bcl5 antibody, BCL5 antibody, BCL6A antibody, LAZ3 antibody, ZBTB27 antibody, ZNF51 antibody, B-cell CLL/lymphoma 6 L homeolog antibody, B-cell CLL/lymphoma 6 antibody, B cell leukemia/lymphoma 6 antibody, bcl6.L antibody, bcl6 antibody, BCL6 antibody, Bcl6 antibody
- Background
- BCL6 (B-cell lymphoma 6) is a 95 kDa zinc finger transcription factor and contains an N-terminal POZ domain. BCL6 is a transcriptional repressor and a master regulator of the germinal center (GC) B cell phenotype controlling its development and growth. BCL-6 modulates IL-4, BCR, and CD40L signals for normal B cell development. Altered BCL6 protein expression is implicated in pathogenesis of diverse human hematologic malignancies, especially in the diffuse large B cell lymphoma (DLBCL), the most common lymphoma in adults. BCL6 suppresses the expression of p53 (also known as tp53) tumor suppressor gene and modulates DNA damage-induced apoptotic responses in GC B cells.
- Molecular Weight
- 72 kDa
- Gene ID
- 604
- UniProt
- P41182
- Pathways
- Chromatin Binding, Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response, Protein targeting to Nucleus
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