Endoglin antibody (AA 43-287)

Catalog No. ABIN5027184

Product Details anti-Endoglin Antibody

Target: Endoglin (ENG)

Binding Specificity: AA 43-287

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Endoglin antibody is un-conjugated

Application: Western Blotting (WB)

Purification: Protein G Chromatography

Immunogen: A partial length recombinant Endoglin protein (amino acids 43-287) was used as the immunogen for this antibody.

Clone: ABM46D3

Isotype: IgG1 kappa

Application Details

Application Notes: WB: 2-4 μg/mL

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: PBS containing 0.05 % BSA, PH 7.4

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.

Target Details for Endoglin

Target: Endoglin (ENG)

Alternative Name: Endoglin (ENG Products)

Synonyms: ENG antibody, MGC137842 antibody, DKFZp469D0419 antibody, END antibody, HHT1 antibody, ORW1 antibody, AI528660 antibody, AI662476 antibody, CD105 antibody, S-endoglin antibody, endoglin antibody, ENG antibody, Eng antibody

Background: ENG (Endoglin) is an integral membrane glycoprotein that serves as a co receptor for members of the transforming growth factor-beta superfamily of proteins. It is a type I membrane glycoprotein expressed as a disulfide-linked homodimer on human vascular endothelial cells and is implicated in a dominant vascular dysplasia known as hereditary hemorrhagic telangiectasia as well as in preeclampsia. Endoglin suppresses human prostate cancer (PCa) cell invasion. It has been identified as a candidate tumor-suppressor gene in esophageal squamous cell carcinoma (ESCC).

Molecular Weight: 70 kDa

Gene ID: 2022

UniProt: P17813