Endoglin antibody (AA 43-287)
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- Target See all Endoglin (ENG) Antibodies
- Endoglin (ENG)
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Binding Specificity
- AA 43-287
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Reactivity
- Human
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This Endoglin antibody is un-conjugated
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Application
- Western Blotting (WB)
- Purification
- Protein G Chromatography
- Immunogen
- A partial length recombinant Endoglin protein (amino acids 43-287) was used as the immunogen for this antibody.
- Clone
- ABM46D3
- Isotype
- IgG1 kappa
- Top Product
- Discover our top product ENG Primary Antibody
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- Application Notes
- WB: 2-4 μg/mL
- Restrictions
- For Research Use only
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- Concentration
- 0.5 mg/mL
- Buffer
- PBS containing 0.05 % BSA, PH 7.4
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C/-20 °C
- Storage Comment
- Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
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- Target
- Endoglin (ENG)
- Alternative Name
- Endoglin (ENG Products)
- Synonyms
- ENG antibody, MGC137842 antibody, DKFZp469D0419 antibody, END antibody, HHT1 antibody, ORW1 antibody, AI528660 antibody, AI662476 antibody, CD105 antibody, S-endoglin antibody, endoglin antibody, ENG antibody, Eng antibody
- Background
- ENG (Endoglin) is an integral membrane glycoprotein that serves as a co receptor for members of the transforming growth factor-beta superfamily of proteins. It is a type I membrane glycoprotein expressed as a disulfide-linked homodimer on human vascular endothelial cells and is implicated in a dominant vascular dysplasia known as hereditary hemorrhagic telangiectasia as well as in preeclampsia. Endoglin suppresses human prostate cancer (PCa) cell invasion. It has been identified as a candidate tumor-suppressor gene in esophageal squamous cell carcinoma (ESCC).
- Molecular Weight
- 70 kDa
- Gene ID
- 2022
- UniProt
- P17813
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