Cytochrome C antibody
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- Target See all Cytochrome C (CYCS) Antibodies
- Cytochrome C (CYCS) (Cytochrome C, Somatic (CYCS))
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Reactivity
- Human
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This Cytochrome C antibody is un-conjugated
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Application
- Western Blotting (WB)
- Purification
- Protein G Chromatography
- Immunogen
- Full length recombinant Cytochrome C protein was used as the immunogen for this antibody.
- Clone
- ABM30D4
- Isotype
- IgG1 kappa
- Top Product
- Discover our top product CYCS Primary Antibody
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- Application Notes
- WB: 2-4 μg/mL
- Restrictions
- For Research Use only
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- Concentration
- 0.5 mg/mL
- Buffer
- PBS containing 0.05 % BSA, PH 7.4
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C/-20 °C
- Storage Comment
- Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
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- Target
- Cytochrome C (CYCS) (Cytochrome C, Somatic (CYCS))
- Alternative Name
- Cytochrome C (CYCS Products)
- Synonyms
- CYC antibody, HCS antibody, THC4 antibody, cyct antibody, cyc antibody, hcs antibody, CYCS antibody, cytc antibody, CYCSA antibody, CG17903 antibody, Cyt C antibody, Cyt c antibody, Cyt-c2 antibody, CytC-2 antibody, Cytc antibody, Cytc-p antibody, DC4 antibody, DMc01 antibody, Dmel\\CG17903 antibody, cyt c antibody, cyt c-p antibody, cyt-c-p antibody, cyt-c2 antibody, cyt.c antibody, cytochrome c antibody, dc4 antibody, pDMc01 antibody, wu:fk52b01 antibody, zgc:86706 antibody, ENSMUSG00000058927 antibody, cytochrome c, somatic antibody, cytochrome c, somatic S homeolog antibody, Cytochrome c proximal antibody, cytochrome c, somatic b antibody, cytochrome c, somatic pseudogene antibody, cytochrome c-like antibody, cytochrome c antibody, CYCS antibody, cycs.S antibody, cycs antibody, Cycs antibody, Cyt-c-p antibody, cycsb antibody, Gm10053 antibody, LOC100724240 antibody, CYC antibody, LOC100847700 antibody, LOC101107954 antibody, LOC106829744 antibody, LOC106992390 antibody, LOC102085712 antibody
- Background
- Cytochrome C is an inner mitochondrial membrane hemeprotein encoded by CYCS gene. Cytochrome C has two major roles within the cell, firstly, it acts as an electron carrier between Complex III (Cytochrome bc1 complex) and Complex IV (Cytochrome C oxidase). The second important function of Cytochrome C is in apoptosis. In response to extrinsic or intrinsic signals and upon suppression of anti-apoptotic molecules, several pro-apoptotic molecules are activated that disturb the mitochondrial membrane permeability and causes the release of Cytochrome C. Cytochrome C then binds to apoptotic protease activating factor-1 (Apaf-1). This complex interacts with pro-caspase 9 and initiates the caspase cascade resulting in apoptosis. Human Cytochrome C has a molecular mass of 11 kDa. Defect in the CYCS gene is associated with autosomal dominant diseases like thrombocytopenia type 4 (THC4). High levels of Cytochrome C are found in blood leukocytes, kidney, liver, heart and brain.
- Molecular Weight
- 11 kDa
- Gene ID
- 54205
- UniProt
- P99999
- Pathways
- Apoptosis, Caspase Cascade in Apoptosis, Positive Regulation of Endopeptidase Activity
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