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IKBKB antibody
IKBKB
Reactivity: Human
WB
Host: Mouse
Monoclonal
ABM10E6
unconjugated
Product Details anti-IKBKB Antibody
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Target
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IKBKB
(Inhibitor of kappa Light Polypeptide Gene Enhancer in B-Cells, Kinase beta (IKBKB))
Reactivity
All reactivities for IKBKB antibodies
Human
Host
All hosts for IKBKB antibodies
Mouse
Clonality
All clonalities for IKBKB antibodies
Monoclonal
Conjugate
All conjugates for IKBKB antibodies
This IKBKB antibody is un-conjugated
Application
All applications for IKBKB antibodies
Western Blotting (WB)
Purification
Protein G Chromatography
Immunogen
Full length recombinant Ikkb protein was used as the immunogen for this antibody.
Clone
ABM10E6
Isotype
IgG1 kappa
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Alternatives
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Application Details
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Application Notes
WB: 2-4 μg/mL
Restrictions
For Research Use only
Handling
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Concentration
0.5 mg/mL
Buffer
PBS containing 0.05 % BSA, PH 7.4
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
4 °C/-20 °C
Storage Comment
Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
Target Details for IKBKB
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Target
IKBKB
(Inhibitor of kappa Light Polypeptide Gene Enhancer in B-Cells, Kinase beta (IKBKB))
Alternative Name
IKKb (IKBKB Products )
Synonyms
ikk-beta antibody, ikk2 antibody, ikkb antibody, ikkbeta antibody, IKBKB antibody, IKKB antibody, CG4201 antibody, DIK antibody, DLAK antibody, DmIKK antibody, DmIKKBeta antibody, DmIKKb antibody, DmIKKbeta antibody, DmIkkbeta antibody, Dmel\\CG4201 antibody, Dmikkb antibody, Dmikkbeta antibody, IK antibody, IKK antibody, IKK-beta antibody, IKKb antibody, IKKbeta antibody, IRD-5 antibody, IRD5 antibody, Ik antibody, Ikkb antibody, Ikkbeta antibody, Ird-5 antibody, Ird5 antibody, LRK antibody, Lak antibody, anon-89Bd antibody, dIKK antibody, dIKK-beta antibody, dIKKbeta antibody, dLak antibody, dmIKKbeta antibody, ikk antibody, ird antibody, ird5/DmIkk[beta] antibody, IKK2 antibody, NFKBIKB antibody, AIM-1 antibody, AI132552 antibody, IKK-2 antibody, IKK[b] antibody, inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta L homeolog antibody, inhibitor of nuclear factor kappa B kinase subunit beta antibody, I-kappaB kinase beta antibody, inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta antibody, inhibitor of kappaB kinase beta antibody, ikbkb.L antibody, IKBKB antibody, ikbkb antibody, IKKbeta antibody, Ikbkb antibody
Background
IKK-a also known as inhibitor of nuclear factor kappa-B kinase subunit beta is a protein which is encoded by the IKBKB (inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta) gene. IKKB causes dissociation of the inhibitor and activation of NF-kappa-B which is activated by multiple stimuli such as inflammatory cytokines, bacterial or viral products, DNA damages or other cellular stresses. Higher expression of this protein is found in liver, kidney and spleen.
Molecular Weight
80 kDa
Gene ID
3551
UniProt
O14920
Pathways
NF-kappaB Signaling , RTK Signaling , TCR Signaling , TLR Signaling , Fc-epsilon Receptor Signaling Pathway , Neurotrophin Signaling Pathway , Activation of Innate immune Response , Production of Molecular Mediator of Immune Response , Hepatitis C , Toll-Like Receptors Cascades , BCR Signaling , Ubiquitin Proteasome Pathway , S100 Proteins
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