TLR4 antibody

Catalog No. ABIN531973

Product Details anti-TLR4 Antibody

Target: TLR4 (Toll-Like Receptor 4 (TLR4))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This TLR4 antibody is un-conjugated

Application: Flow Cytometry (FACS), Immunoprecipitation (IP), Immunofluorescence (IF), Immunocytochemistry (ICC)

Purpose: Mouse monoclonal antibody raised against full length recombinant TLR4.

Cross-Reactivity: Human

Immunogen: Recombinant protein corresponding to full length human TLR4.

Clone: HTA125

Isotype: IgG2a

Application Details

Application Notes: The optimal working dilution should be determined by the end user.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In PBS

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.

References for anti-TLR4 antibody (ABIN531973)

Prabha, Rajashree, Sulochana: "TLR2 and TLR4 expression on the immune cells of tuberculous pleural fluid." in: Immunology letters, Vol. 117, Issue 1, pp. 26-34, (2008) (PubMed).

Wong, Cheung, Ip, Lam: "Intracellular signaling mechanisms regulating toll-like receptor-mediated activation of eosinophils." in: American journal of respiratory cell and molecular biology, Vol. 37, Issue 1, pp. 85-96, (2007) (PubMed).

Basu, Pathak, Banerjee, Pathak, Bhattacharyya, Yang, Talarico, Kundu, Basu: "Execution of macrophage apoptosis by PE_PGRS33 of Mycobacterium tuberculosis is mediated by Toll-like receptor 2-dependent release of tumor necrosis factor-alpha." in: The Journal of biological chemistry, Vol. 282, Issue 2, pp. 1039-50, (2007) (PubMed).

Zanoni, Navone, Lunardi, Tridente, Bason, Sivori, Beri, Dolcino, Valletta, Corrocher, Puccetti: "In celiac disease, a subset of autoantibodies against transglutaminase binds toll-like receptor 4 and induces activation of monocytes." in: PLoS medicine, Vol. 3, Issue 9, pp. e358, (2006) (PubMed).

Shahrara, Park, Temkin, Jarvis, Volin, Pope: "RANTES modulates TLR4-induced cytokine secretion in human peripheral blood monocytes." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 177, Issue 8, pp. 5077-87, (2006) (PubMed).

Target Details for TLR4

Target: TLR4 (Toll-Like Receptor 4 (TLR4))

Alternative Name: CD284 / TLR4 (TLR4 Products)

Synonyms: ARMD10 antibody, CD284 antibody, TLR-4 antibody, TOLL antibody, Lps antibody, Ly87 antibody, Ran/M1 antibody, Rasl2-8 antibody, toll like receptor 4 antibody, toll-like receptor 4 antibody, TLR4 antibody, Tlr4 antibody

Gene ID: 7099

Pathways: TLR Signaling, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Toll-Like Receptors Cascades, Inflammasome, S100 Proteins