HLA-ABC antibody (PE)
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- Target See all HLA-ABC Antibodies
- HLA-ABC
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Reactivity
- Human
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This HLA-ABC antibody is conjugated to PE
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Application
- Flow Cytometry (FACS)
- Purpose
- Mouse monoclonal antibody raised against native HLA-Class I.
- Specificity
- This antibody reacts with all human classical MHC Class I molecules in native cell-surface forms (e.g. it recognizes native HLA-A2 in cytofluorometry and immunoprecipitation but not in Western blot). This antibody is positive in Western blot (non-reducing conditions) only with most HLA-B and HLA-C molecules, but not HLA-A.
- Immunogen
- Native purified HLA-Class I from PHA-activated peripheral blood lymphocytes.
- Clone
- MEM-147
- Isotype
- IgG1
- Top Product
- Discover our top product HLA-ABC Primary Antibody
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- Application Notes
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Flow Cytometry (5 μg/mL)
The optimal working dilution should be determined by the end user. - Restrictions
- For Research Use only
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- Concentration
- 0.1 mg/mL
- Buffer
- In PBS (0.2 % BSA, 0.09 % sodium azide)
- Storage
- 4 °C
- Storage Comment
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Store in the dark at 4°C. Do not freeze.
Avoid prolonged exposure to light.
Aliquot to avoid repeated freezing and thawing.
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Expression of HLA-G in human cornea, an immune-privileged tissue." in: Human immunology, Vol. 64, Issue 11, pp. 1039-44, (2003) (PubMed).
: "The epitope recognized by pan-HLA class I-reactive monoclonal antibody W6/32 and its relationship to unusual stability of the HLA-B27/beta2-microglobulin complex." in: Immunogenetics, Vol. 53, Issue 6, pp. 440-6, (2001) (PubMed).
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Expression of HLA-G in human cornea, an immune-privileged tissue." in: Human immunology, Vol. 64, Issue 11, pp. 1039-44, (2003) (PubMed).
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- Target
- HLA-ABC
- Alternative Name
- HLA Class I ABC (HLA-ABC Products)
- Synonyms
- HLAA antibody, major histocompatibility complex, class I, A antibody, HLA-A antibody
- Pathways
- TCR Signaling, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Cancer Immune Checkpoints
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