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HLA-ABC antibody (PE)

HLA-ABC Reactivity: Human FACS Host: Mouse Monoclonal MEM-147 PE
Catalog No. ABIN536589
  • Target See all HLA-ABC Antibodies
    HLA-ABC
    Reactivity
    • 69
    • 23
    • 14
    • 13
    • 12
    • 11
    • 11
    • 10
    • 8
    • 7
    • 7
    • 6
    • 1
    • 1
    • 1
    Human
    Host
    • 57
    • 9
    • 3
    Mouse
    Clonality
    • 59
    • 9
    Monoclonal
    Conjugate
    • 31
    • 7
    • 6
    • 6
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This HLA-ABC antibody is conjugated to PE
    Application
    • 53
    • 18
    • 18
    • 11
    • 10
    • 10
    • 8
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Flow Cytometry (FACS)
    Purpose
    Mouse monoclonal antibody raised against native HLA-Class I.
    Specificity
    This antibody reacts with all human classical MHC Class I molecules in native cell-surface forms (e.g. it recognizes native HLA-A2 in cytofluorometry and immunoprecipitation but not in Western blot). This antibody is positive in Western blot (non-reducing conditions) only with most HLA-B and HLA-C molecules, but not HLA-A.
    Immunogen
    Native purified HLA-Class I from PHA-activated peripheral blood lymphocytes.
    Clone
    MEM-147
    Isotype
    IgG1
    Top Product
    Discover our top product HLA-ABC Primary Antibody
  • Application Notes
    Flow Cytometry (5 μg/mL)
    The optimal working dilution should be determined by the end user.
    Restrictions
    For Research Use only
  • Concentration
    0.1 mg/mL
    Buffer
    In PBS (0.2 % BSA, 0.09 % sodium azide)
    Storage
    4 °C
    Storage Comment
    Store in the dark at 4°C. Do not freeze.
    Avoid prolonged exposure to light.
    Aliquot to avoid repeated freezing and thawing.
  • Le Discorde, Moreau, Sabatier, Legeais, Carosella: "Expression of HLA-G in human cornea, an immune-privileged tissue." in: Human immunology, Vol. 64, Issue 11, pp. 1039-44, (2003) (PubMed).

    Tran, Ivanyi, Hilgert, Brdicka, Pla, Breur, Flieger, Ivasková, Horejsí: "The epitope recognized by pan-HLA class I-reactive monoclonal antibody W6/32 and its relationship to unusual stability of the HLA-B27/beta2-microglobulin complex." in: Immunogenetics, Vol. 53, Issue 6, pp. 440-6, (2001) (PubMed).

  • Target
    HLA-ABC
    Alternative Name
    HLA Class I ABC (HLA-ABC Products)
    Synonyms
    HLAA antibody, major histocompatibility complex, class I, A antibody, HLA-A antibody
    Pathways
    TCR Signaling, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Cancer Immune Checkpoints
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