Western Blot (1:500-1:2000) ELISA (1:10000) The optimal working dilution should be determined by the end user.
Restrictions
For Research Use only
Format
Liquid
Buffer
In ascites
Storage
-20 °C
Storage Comment
Store at -20°C. Aliquot to avoid repeated freezing and thawing.
Shi, Cooper, Yu: "A constitutively active Lck kinase promotes cell proliferation and resistance to apoptosis through signal transducer and activator of transcription 5b activation." in: Molecular cancer research : MCR, Vol. 4, Issue 1, pp. 39-45, (2006) (PubMed).
Stachlewitz, Hart, Bettencourt, Kebede, Schwartz, Ratnofsky, Calderwood, Waegell, Hirst: "A-770041, a novel and selective small-molecule inhibitor of Lck, prevents heart allograft rejection." in: The Journal of pharmacology and experimental therapeutics, Vol. 315, Issue 1, pp. 36-41, (2005) (PubMed).
Hawash, Kesavan, Magee, Geahlen, Harrison: "The Lck SH3 domain negatively regulates localization to lipid rafts through an interaction with c-Cbl." in: The Journal of biological chemistry, Vol. 277, Issue 7, pp. 5683-91, (2002) (PubMed).
Target
LCK
(Lymphocyte-Specific Protein tyrosine Kinase (LCK))